All AbMole products are for research use only, cannot be used for human consumption.
Species: Human
Expression system: E. coli
Purity: SDS-PAGE, > 95%
Endotoxin: protein < 0.2 EU/μg was determined by gel coagulation
Apparent molecular weight: ~8.9 kDa, sdS-PAGE under reduction conditions
Storage and stability: After receiving, the product remains stable at temperatures below -70°C for up to 6 months. After recombination, the product should be stable at 4°C for 1 week or -20°C for 3 months. For long-term preservation, carrier protein (e.g. 0.1% BSA) is recommended. Avoid repeated freeze-thaw cycles.
Bioactivity: CHO cells were transfected with human CCL8 receptor CCR5, and ED50 < 0.5µg/ mL was detected by FLIPR method, corresponding specific activity was > 2.0 × 103 units /mg. McP-2 and McP-1 have 60% homology, and both egg whites can be dimerized reversibly. The main receptors of McP-2 are G protein-coupled receptors CCR1 and CCR5. McP-2 is a potential target of HIV-1-infected human glial cells because it may play a role in regulating the spread of the virus in the brain. Recently, mouse McP-2 has been identified as a novel CCR8 agonist that is expressed in the skin and plays a role in eosinophilic inflammation.
| Solubility (25°C) | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml. |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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