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Recombinant Mouse IL-10 (CHO)

Cat. No. M15109

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse IL-10 (CHO) Structure
Synonym:

Mouse Interleukin-10 Protein

Size Price Availability Quantity
10ug USD 250  USD250 In stock
50ug USD 750  USD750 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Recombinant Mouse IL-10 (CHO) belongs to the IL-10 family and shares more than 80% sequence homology with the Epstein-Barr Virus protein BCRFI. It is usually secreted as a homodimer and, upon binding to its receptor, inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF, by activated macrophages and Th2 cells. Recombinant Mouse IL-10 also displays the ability to suppress Antigen-Presenting Cell (APC) function.

ED50 < 0.2 ng/ml, measured in a cell proliferation assay using MC/9 cells.


Accession #: P18893

Apparent Molecular Weight: 21~23 kDa, on SDS-PAGE under reducing conditions.

Lyophilized after extensive dialysis against PBS.

Chemical Information
Solubility (25°C) Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Mira Jung, et al. Basic Res Cardiol. IL-10 improves cardiac remodeling after myocardial infarction by stimulating M2 macrophage polarization and fibroblast activation

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Keywords: Recombinant Mouse IL-10 (CHO), Mouse Interleukin-10 Protein supplier, Cytokines and Growth Factors, inhibitors, activators

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