Free shipping on all orders over $ 500
Expression host: HEK293 cells
Molecular weight: the predicted molecular weight is 12.8 kD
Purity: >95% Analysis was performed by SDS-PAGE gel and HIGH performance liquid chromatography
Endotoxin: <0.1EU/μg (gel method)
Storage and stability: storage temperature: 2-8℃, lyophilized preparation can be stored at 2-8℃ for 24 months. If it is needed to be packaged separately, it can be dissolved with water for injection, normal saline, medium or PBS. After dissolved, it can be packaged separately into small portions and stored at -20℃ for 6 months and -80℃ for 12 months to avoid repeated freeze-thaw.
Bioactivity: Cell proliferation was measured with MO7e human megakaryocytic leukemia cells with an ED50 of 7-28 ng/mL
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Molecular Weight | |
| Formula | |
| CAS Number | |
| Purity | >95% , Endotoxin <0.1EU/μg |
| Solubility | N/A |
| Storage | 2-8℃ |
| Related Cytokines Products |
|---|
| DKK-1 (Mammalian,N-8His)
Recombinant Human Dickkopf-related protein 1 is produced by our Mammalian expression system and the target gene encoding Thr32-His266 is expressed with a 8His tag at the N-terminus. |
| FGF-basic, Rat（E. coli）
FGF-basic, Rat（E. coli） Expressed with an n-terminal Gly. FGF-basic (Pro10-Ser154) Accession # P13109. Bioactivity: ED50 < 0.25 ng/ mL, measured by 3T3 cell proliferation method, corresponding to > 4.0 × 106 units /mg. |
| TNF-α, Human (E. coli)
TNF-α, Human (E. coli) Protein structure: TNF-α (VAL77-LEU233) Accession # P01375. Bioactivity: ED50 < 30.0 pg/ mL, measured in cytotoxicity assay of L-929 mouse fibrosarcoma cells in the presence of metabolic inhibitor actinomycin D, corresponding specific activity > 3.3 × 107 units /mg. |
| BMP-2, Human（E. coli）
BMP-2, Human（E. coli） Protein structure: BMP-2 (GLN283-ARG396) Accession # P12643. Biological activity: Experiment 1: To determine its ability to induce alkaline phosphatase production in ATDC-5 cells. The ED50 for this effect is generally 0.07-0.2µg/ mL. Experiment 2: The ability of inducing ALKALINE phosphatase production in C2C12 cells was determined. The ED50 for this effect is usually 0.2-1µg/ mL. |
| SCF, Human (P. pastoris)
SCF, Human (P. pastoris) The protein was Expressed with an n-terminal Met. SCF (Glu26-Ala189) Accession # P21583-1. Biological activity: ED50 was < 2.0 ng/ mL by dose-dependent tF-1 cell stimulation, corresponding specific activity was 5 × 105IU /mg. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.
