All AbMole products are for research use only, cannot be used for human consumption.
Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating peptide whose RGD motif interacts with alphav-integrins and activates neurofibrillary protein 1 (NRP-1) to transform the solid tumor microenvironment into a temporary drug pipeline. Sequence Shortening: Ac-CRGDKGPDC-NH2 (Disulfide bridge: Cys1-Cys9).
| Molecular Weight | 989.09 |
| Formula | C37H60N14O14S2 |
| CAS Number | 2580154-02-3 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Integrin Products |
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| Volociximab
Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 (EC50=0.2 nM). Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs). |
| GSK 3008348 hydrochloride
GSK 3008348 hydrochloride is a small molecule integrin αvβ6 antagonist. |
| HSDVHK-NH2
HSDVHK-NH2 is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC50 of 1.74 pg/mL (2.414 pM). |
| LDV
LDV, a tripeptide, is a non-fluorescent analog of LDV-FITC. |
| Cyclo(RADfK)
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis. |
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Products are for research use only. Not for human use. We do not sell to patients.
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