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Recombinant Human 4-1BB Protein (HEK293)

Cat. No. M11390

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human 4-1BB Protein (HEK293) Structure
Synonym:

TNFRSF9、4-1BB、CD137、CDw137、ILA

Size Price Availability Quantity
10ug USD 150  USD150 In stock
20ug USD 250  USD250 In stock
50ug USD 350  USD350 In stock
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Quality Control & Documentation
  • Purity: >95% , Endotoxin <0.1EU/μg
  • COA
  • MSDS
Biological Activity

Expression host: human HEK293 cells
Source: Human
Molecular weight: Human 4-1BB Protein contains 162 amino acids and has a predicted theoretical molecular weight of 19 kD
Purity: ≥95% Was analyzed by SDS-PAGE gel and HIGH performance liquid chromatography
Endotoxin: < 0.1EU/μg
Storage and stability: Freeze-dried samples can be stored at 4℃ for 24 months, dissolved liquid can be stored at -20℃ for 6-12 months, and avoid repeated freeze-thaw


Bioactivity: the concentration of the ligand (FC tag) fixing human 4-1BB at 1ug/mL (100uL/ well) can bind human 4-1BB (HIS tag) in a linear range of 0.2-10 ng/mL

Chemical Information
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shannon K Oda, et al. J Exp Med. A Fas-4-1BB fusion protein converts a death to a pro-survival signal and enhances T cell therapy

[2] Angela C Boroughs, et al. Mol Ther. A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq

[3] Marta Trb, et al. J Immunother Cancer. Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer

[4] Nathalie Bonnefoy, et al. Med Sci (Paris). [Next generation of anti-immune checkpoints antibodies]

[5] Omkar U Kawalekar, et al. Immunity. Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

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Keywords: Recombinant Human 4-1BB Protein (HEK293), TNFRSF9、4-1BB、CD137、CDw137、ILA supplier, Cytokines and Growth Factors, inhibitors, activators

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