| Cat.No. | Name | Information |
|---|---|---|
| M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
| M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
| M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
| M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist, with pIC50 and pKd of 8.73 and 9.3, respectively. |
| M2378 | Alverine Citrate | Alverine citrate is a compound used for functional gastrointestinal disorders. |
| M2279 | Citalopram hydrobromide | Citalopram (Celexa, Cipramil) is a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (CNS). |
| M2266 | Pizotifen malate | Pizotifen malate is a potent 5-HT2 receptor antagonist, with a high affinity for 5-HT1C binding site. |
| M2262 | Mianserin hydrochloride | Mianserin HCl is a tetracyclic antidepressant compound. |
| M2231 | Dimebon dihydrochloride | Latrepirdine is an antihistamine compound. |
| M2175 | Palonosetron hydrochloride | Palonosetron hydrochloride is a novel antiemetic 5-HT3-receptor antagonist. |
| M2155 | (1S-cis)-Milnacipran Hydrochloride | (1S-cis)-Milnacipran hydrochloride is a selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. |
| M2146 | Prucalopride | Prucalopride is a potent, selective and specific serotonin 5-HT4 receptor agonist with enterokinetic properties. |
| M2134 | Vortioxetine hydrobromide | Vortioxetine hydrobromide (Lu AA21004) is a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist, a 5-HT1B receptor partial agonist, a 5-HT1A receptor agonist and a 5-HT transporter (5-HTT) inhibitor in vitro. |
| M1930 | Granisetron hydrochloride | Granisetron hydrochloride is a potent and selective 5-HT3 receptor antagonist that possesses potent antiemetic activity. |
| M1574 | Iloperidone | Iloperidone, a serotonin (5-HT2) receptor inhibitor, is used to study schizophrenia. |
| M1565 | Quetiapine sulfoxide | Quetiapine sulfoxide is a 5-HT receptor agonist with a pEC50 value of 4.77 for human 5-HT1A. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 value of 6.33 for human D2. |
| M1564 | Quetiapine Sulfone | Quetiapine Sulfone is a 5-HT receptor agonist with a pEC50 value of 4.77 for human 5-HT1A. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 value of 6.33 for human D2. |
| M1559 | Clomipramine Hydrochloride | Clomipramine HCl is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively. |
| M1454 | Buspirone | Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. |
| M56103 | AS19 | AS19 is a potent, selective 5-HT7 receptor agonist with an IC50 value of 0.83 nM and a Ki of 0.6 nM. |
| M56102 | CP94253 | CP94253 is a selective, orally active agonist for serotonin receptor 1B (5-HT1B), through competitive binding with iodocyanopindolol (ICP) to the 5-HT1 receptor. |
| M56101 | RS 39604 | RS 39604 is a potent, selective, and orally active 5-HT4 receptor antagonist with a pKi of 9.1 in guinea pig striatal membranes. |
| M56100 | GR127935 | GR127935 is a selective 5-HT1D receptor antagonist. |
| M56099 | SB-699551 | SB-699551 is a potent and selective 5-HT5A antagonist with a pKi of 8.3. |
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