| Cat.No. | Name | Information |
|---|---|---|
| M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
| M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
| M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
| M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist. |
| M2134 | Vortioxetine hydrobromide | Vortioxetine hydrobromide (Lu AA21004) is a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist, a 5-HT1B receptor partial agonist, a 5-HT1A receptor agonist and a 5-HT transporter (5-HTT) inhibitor in vitro. |
| M1930 | Granisetron hydrochloride | Granisetron hydrochloride is a potent and selective 5-HT3 receptor antagonist that possesses potent antiemetic activity. |
| M1574 | Iloperidone | Iloperidone, a serotonin (5-HT2) receptor inhibitor, is used to study schizophrenia. |
| M1565 | Quetiapine sulfoxide | Quetiapine sulfoxide is a 5-HT receptor agonist with a pEC50 value of 4.77 for human 5-HT1A. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 value of 6.33 for human D2. |
| M1564 | Quetiapine Sulfone | Quetiapine Sulfone is a 5-HT receptor agonist with a pEC50 value of 4.77 for human 5-HT1A. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 value of 6.33 for human D2. |
| M1559 | Clomipramine Hydrochloride | Clomipramine HCl is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively. |
| M1454 | Buspirone | Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. |
| M54819 | TC-2153 | TC-2153 is a selective inhibitor of striatal-enriched protein tyrosine phosphatase (STEP). TC-2153 also inhibits 5-HT2A receptor-mediated signaling. |
| M54777 | Gentisein | Gentisein (NSC-329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 µM. |
| M54692 | MM120 | MM120 is a synthetic tryptamine that is also a partial agonist at the 5-hydroxytryptamine 2A (5-HT2A) receptor. It can be used in studies related to GAD and attention deficit hyperactivity disorder (ADHD). |
| M54596 | SB 258741 hydrochloride | SB 258741 hydrochloride is a specific 5-HT7 receptor antagonist for schizophrenia. |
| M54595 | 5-HT1A antagonist 1 | 5-HT1A antagonist 1 is a potent and selective 5-HT1A receptor antagonist with a Ki value of 35 nM.5-HT1A antagonist 1 can be used in the study of central nervous system disorders. |
| M54513 | Nemifitide diTFA | Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. |
| M53845 | 4-Chloro-L-phenylalanine | 4-Chloro-L-phenylalanine (L-PCPA) is a 5-HT biosynthesis inhibitor. |
| M53286 | CART(62-76)(human, rat) | CART(62-76)(human,rat) is a neuropeptide (62-76 residues of the CART peptide) with neurotransmitter-like effects. |
| M49944 | GM2505 | GM2505 is a novel 5-HT2A receptor agonist for studies related to treatment-refractory depression (TRD) and depressive disorder (MDD). |
| M49454 | Gepirone Hydrochloride | Gepirone Hydrochloride is a first-in-class, selective, affinity-based, orally active 5-HT1A receptor partial agonist as well as a 5-HT2A receptor antagonist for use in studies related to anxiety, depression, and chronic kidney disease. |
| M49351 | AX-1602 | AX-1602 is a 5-HT1A receptor antagonist, adrenergic receptor ADRA2 agonist, and cannabinoid receptor CB1 antagonist for studies related to atopic dermatitis, psoriasis, and vitiligo. |
| M41755 | MRS7925 | MRS7925 is a 5-HT2BR antagonist (Ki: 17 nM). |
| M41754 | 5-HT6 agonist 1 | 5-HT6 agonist 1 is a 5-HT6 agonist (Ki: 5 nM). |
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