| Cat.No. | Name | Information |
|---|---|---|
| M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
| M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
| M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
| M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist, with pIC50 and pKd of 8.73 and 9.3, respectively. |
| M41741 | Dehydroaripiprazole hydrochloride | Dehydroaripiprazole (OPC-14857) hydrochloride is an active metabolite of Aripiprazole. |
| M41740 | 5-HT2C agonist-3 free base | 5-HT2C agonist-3 ((+)-19) free base is a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM). |
| M41739 | Dehydro Palonosetron | Dehydro Palonosetron (RS 42358-197) is a potent, seslective and orally active 5-HT3 receptor antagonist. |
| M41738 | 5-HT2 agonist-1 | 5-HT2 agonist-1 is a 5-HT2A & 5-HT2B & 5-HT2C agonist, with IC50s of 10 nM, 8.3, and 1.6 nM respectively. |
| M41737 | AVN-322 | AVN-322 is an orally active, highly selective 5-HT6Rantagonist for central nervous system disease research. |
| M41736 | 5-HT2A&5-HT2C agonist-1 | 5-HT2A&5-HT2C agonist-1 is a 5-HT2A & 5-HT2C agonist, with IC50s of 196 nM and 0.9 nM respectively. |
| M41735 | 5-HT2 agonist-1 free base | 5-HT2 agonist-1 free base is a 5-HT2A & 5-HT2B & 5-HT2C agonist, with IC50s of 10 nM, 8.3, and 1.6 nM respectively. |
| M41734 | Amitriptylinoxide | Amitriptylinoxide (Equilibrin) is an analogue and metabolite of amitriptyline with similar antidepressant efficacy. |
| M41733 | AC-90179 | AC-90179 is a selective 5-HT2A receptor inverse agonist (Ki = 2.1 nM) and 5-HT2C antagonist, a potential antipsychotic compound. |
| M41732 | WAY-181187 hydrochloride | WAY-181187 (SAX-187) hydrochloride is a potent and selective full 5-HT6 receptor agonist with a Ki of 2.2 nM and an EC50 of 6.6 nM. |
| M41731 | FFN246 | FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. |
| M41730 | 5-HT2A receptor agonist-3 | 5-HT2A receptor agonist-3 is the most selective agonist for the human 5-HT2A receptor yet discovered, with a Ki of 2.5 nM. |
| M40565 | Azasetron hydrochloride | Azasetron hydrochloride is the hydrochloride form of Azasetron and is also an orally active 5-HT3 receptor antagonist that can be used in studies related to ear disorders such as sudden hearing loss. |
| M39186 | 5-Methoxytryptamine hydrochloride | 5-Methoxytryptamine hydrochloride, a metabolite of Melatonin, is a nonselective 5-HT receptor agonist. 5-Methoxytryptamine hydrochloride has no affinity for the 5-HT3 receptor. 5-Methoxytryptamine hydrochloride is also a potent antioxidant and has radioprotective action. |
| M38952 | Nantenine | Nantenine is a serotonergic receptor antagonist. Nantenine selectively inhibits the contractile response of tissues to serotonin. Nantenine can be isolated from Nandina domestica. |
| M38951 | 2'-O-Methylisoliquiritigenin | 2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway. |
| M31289 | Liafensine | Liafensine (BMS-820836) is a selective triple reuptake inhibitor of serotonin (5-HT), norepinephrine and dopamine. It may be used in studies related to depression. |
| M31208 | Desvenlafaxine fumarate | Desvenlafaxine (O-Desmethylvenlafaxine) fumarate is a selective serotonin and norepinephrine reuptake inhibitor. |
| M31207 | Ampreloxetine | Ampreloxetine (TD-9855) is a potent and orally active norepinephrine (NE) and serotonin 5-HT inhibitor. Ampreloxetine has the potential for the research of neurogenic orthostatic hypotension. |
| M31167 | Citalopram | Citalopram is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor (SSRI) that can be used in studies related to depression. |
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