| Cat.No. | Name | Information |
|---|---|---|
| M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
| M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
| M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
| M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist, with pIC50 and pKd of 8.73 and 9.3, respectively. |
| M3006 | Sertraline hydrochloride | Sertraline hydrochloride is a 5-HT antagonist with Ki of 13 nM. |
| M56086 | DV-7028 hydrochloride | DV-7028 is a selective 5-hydroxytryptamine2 (5-HT2) receptor antagonist. |
| M56085 | LY334370 hydrochloride | LY334370 hydrochloride is a selective 5-HT1F receptor agonist with a Kd value of 0.446 nM. |
| M56084 | SB 243213 hydrochloride | SB 243213 hydrochloride is an orally active, selective and high-affinity 5-HT2C receptor antagonist with a pKi of 9.37 and a pKb of 9.8 for human 5-HT2C receptor. |
| M56083 | SB-224289 hydrochloride | SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect. |
| M56082 | LY 344864 hydrochloride | LY 344864 hydrochloride is a selective, orally active 5-HT1F receptor agonist with a Ki of 6 nM. |
| M56081 | SB 258719 hydrochloride | SB 258719 hydrochloride is a selective 5-HT7 receptor antagonist displayed high affnity (pKi=7.5) for the receptor. |
| M56080 | Zacopride hydrochloride | Zacopride hydrochloride is a highly potent 5-HT3 receptor antagonist with Kis of 0.38 and 373 nM for 5-HT3 and 5-HT4 receptor, respectively. |
| M56079 | Anpirtoline hydrochloride | Anpirtoline hydrochloride is a hydrochloride of anpirtoline. |
| M56078 | SB 243213 dihydrochloride | SB 243213 dihydrochloride is an orally active, selective and high-affinity 5-HT2C receptor antagonist with a pKi of 9.37 and a pKb of 9.8 for human 5-HT2C receptor. |
| M56077 | (R)-Viloxazine hydrochloride | (R)-Viloxazine hydrochloride is a less active R-isomer of Viloxazine hydrochloride. |
| M56076 | Tedatioxetine hydrobromide | Tedatioxetine (Lu AA24530) hydrobromide acts as a serotonin and norepinephrine (NE)-preferring triple reuptake inhibitor (TRI) and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist. |
| M56075 | R(+)-8-OH-DPAT hydrobromide | R(+)-8-OH-DPAT ((R)-8-Hydroxy-2-dipropylaminotetralin) hydrobromide is a potent 5-HT1A agonist. |
| M56074 | NPS ALX Compound 4a dihydrochloride | NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM. |
| M54819 | TC-2153 | TC-2153 is a selective inhibitor of striatal-enriched protein tyrosine phosphatase (STEP). TC-2153 also inhibits 5-HT2A receptor-mediated signaling. |
| M54777 | Gentisein | Gentisein (NSC-329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 µM. |
| M54692 | MM120 | MM120 is a synthetic tryptamine that is also a partial agonist at the 5-hydroxytryptamine 2A (5-HT2A) receptor. It can be used in studies related to GAD and attention deficit hyperactivity disorder (ADHD). |
| M54596 | SB 258741 hydrochloride | SB 258741 hydrochloride is a specific 5-HT7 receptor antagonist for schizophrenia. |
| M54595 | 5-HT1A antagonist 1 | 5-HT1A antagonist 1 is a potent and selective 5-HT1A receptor antagonist with a Ki value of 35 nM.5-HT1A antagonist 1 can be used in the study of central nervous system disorders. |
| M54513 | Nemifitide diTFA | Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. |
| M53845 | 4-Chloro-L-phenylalanine | 4-Chloro-L-phenylalanine (L-PCPA) is a 5-HT biosynthesis inhibitor. |
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