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5-HT Receptor 5-hydroxytryptamine receptor

Cat.No.  Name Information
M2048 Sumatriptan succinate Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache.
M3417 Clozapine Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis.
M2821 Lorcaserin hydrochloride Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM.
M5656 Fluoxetine hydrochloride Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
M14577 Fluoxetine Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research.
M3659 Pimavanserin Pimavanserin is a selective serotonin 5-HT2A inverse agonist, with pIC50 and pKd of 8.73 and 9.3, respectively.
M56098 BRL-15572  BRL-15572 is a selective antagonist of h5-HT1D, displays high affinity for h5-HT1D receptors.
M56097 SB 243213  SB 243213 is an orally active, selective and high-affinity 5-HT2C receptor antagonist with a pKi of 9.37 and a pKb of 9.8 for human 5-HT2C receptor.
M56096 BGC20-761  BGC20-761 is a selecvtive 5-HT6 and dopamine receptor antagonist (human receptor Ki values: 5-HT6 (20 nM), 5-HT2A (69 nM), D2 (140 nM).
M56095 Ro60-0175  Ro60-0175 is a potent and selective agonist of 5-HT2C receptor.
M56094 GR 125743  GR 125743 is a selective 5-HT1B/1D receptor antagonist, with pKis of 8.85 and 8.31 for wild-type h5-HT1B and wild-type h5-HT1D, respectively.
M56093 SB-216641A SB-216641A (SB-216641 hydrochloride) is a selective antagonist of 5-HT1B/D receptor.
M56092 Pumosetrag  F6&" is a bioavtive small molecular compound."
M56091 Tedatioxetine Tedatioxetine (Lu AA24530) acts as a serotonin and norepinephrine (NE)-preferring triple reuptake inhibitor (TRI) and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist.
M56090 GR125487 sulfamate  GR125487 sulfamate is an orally active and selective antagonist of 5-HT4R.
M56089 FR260010 free base  FR260010 free base is a selective 5-HT2C receptor antagonist, with a Ki value of 1.1 nM.
M56088 Ro60-0175 fumarate  Ro60-0175 fumarate is a potent and selective agonist of 5-HT2C receptor.
M56087 CP94253 hydrochloride  CP94253 hydrochloride is a potent and selective agonist of 5-HT1B receptor (Ki= 2 nM in a radioligand binding assay).Ki values for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors are 89, 49, 860, and 1600 nM respectively.
M56086 DV-7028 hydrochloride  DV-7028 is a selective 5-hydroxytryptamine2 (5-HT2) receptor antagonist.
M56085 LY334370 hydrochloride  LY334370 hydrochloride is a selective 5-HT1F receptor agonist with a Kd value of 0.446 nM.
M56084 SB 243213 hydrochloride  SB 243213 hydrochloride is an orally active, selective and high-affinity 5-HT2C receptor antagonist with a pKi of 9.37 and a pKb of 9.8 for human 5-HT2C receptor.
M56083 SB-224289 hydrochloride SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect.
M56082 LY 344864 hydrochloride  LY 344864 hydrochloride is a selective, orally active 5-HT1F receptor agonist with a Ki of 6 nM.
M56081 SB 258719 hydrochloride  SB 258719 hydrochloride is a selective 5-HT7 receptor antagonist displayed high affnity (pKi=7.5) for the receptor.
M56080 Zacopride hydrochloride  Zacopride hydrochloride is a highly potent 5-HT3 receptor antagonist with Kis of 0.38 and 373 nM for 5-HT3 and 5-HT4 receptor, respectively.
M56079 Anpirtoline hydrochloride Anpirtoline hydrochloride is a hydrochloride of anpirtoline.




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