| Cat.No. | Name | Information |
|---|---|---|
| M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
| M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
| M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
| M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist, with pIC50 and pKd of 8.73 and 9.3, respectively. |
| M3006 | Sertraline hydrochloride | Sertraline hydrochloride is a 5-HT antagonist with Ki of 13 nM. |
| M49454 | Gepirone Hydrochloride | Gepirone Hydrochloride is a first-in-class, selective, affinity-based, orally active 5-HT1A receptor partial agonist as well as a 5-HT2A receptor antagonist for use in studies related to anxiety, depression, and chronic kidney disease. |
| M49351 | AX-1602 | AX-1602 is a 5-HT1A receptor antagonist, adrenergic receptor ADRA2 agonist, and cannabinoid receptor CB1 antagonist for studies related to atopic dermatitis, psoriasis, and vitiligo. |
| M41755 | MRS7925 | MRS7925 is a 5-HT2BR antagonist (Ki: 17 nM). |
| M41754 | 5-HT6 agonist 1 | 5-HT6 agonist 1 is a 5-HT6 agonist (Ki: 5 nM). |
| M41753 | NAN-190 | NAN-190 is a serotonin receptor 5-HT antagonist. |
| M41752 | PNU109291 | PNU109291 is a potent and selective 5-HT1D agonist. |
| M41751 | GSK215083 | GSK215083 is a high affinity 5-HT6 receptor antagonist. |
| M41750 | 5-HT3 antagonist 4 | 5-HT3 antagonist 4 is a 5-HT3 receptor (5HT3R) antagonist. |
| M41749 | GR 55562 hydrochloride | GR 55562 hydrochloride is a selective 5-HT1B receptor antagonist. |
| M41748 | 5-HT6R antagonist 1 | 5-HT6R antagonist 1 is a 5-HT6R antagonist (Ki: 5 nM). |
| M41747 | GR 55562 dihydrochloride | GR 55562 (dihydrochloride) is a selective 5-HT1B receptor antagonist. |
| M41746 | JPC0323 | JPC0323 is a dual 5-HT2C/5-HT2A receptor positive allosteric modulator. |
| M41745 | SB-224289 | SB-224289 is a selective 5-HT1B receptor antagonist, with anxiolytic effect. |
| M41744 | m-CPBG hydrochloride | m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride is a selective 5-HT3 agonist. |
| M41743 | 5-HT2C agonist-3 | 5-HT2C agonist-3 ((+)-19) is a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM). |
| M41742 | Indisetron dihydrochloride | Indisetron dihydrochloride is a 5-HT3 receptor antagonist with anti-emetic activity. |
| M41741 | Dehydroaripiprazole hydrochloride | Dehydroaripiprazole (OPC-14857) hydrochloride is an active metabolite of Aripiprazole. |
| M41740 | 5-HT2C agonist-3 free base | 5-HT2C agonist-3 ((+)-19) free base is a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM). |
| M41739 | Dehydro Palonosetron | Dehydro Palonosetron (RS 42358-197) is a potent, seslective and orally active 5-HT3 receptor antagonist. |
| M41738 | 5-HT2 agonist-1 | 5-HT2 agonist-1 is a 5-HT2A & 5-HT2B & 5-HT2C agonist, with IC50s of 10 nM, 8.3, and 1.6 nM respectively. |
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