| Cat.No. | Name | Information |
|---|---|---|
| M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
| M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
| M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
| M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist. |
| M20473 | Dolasetron | Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. |
| M20467 | Paroxetine mesylate | Paroxetine Mesylate is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties. |
| M20437 | Perospirone hydrochloride | Perospirone is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist. |
| M20417 | Flibanserin | Flibanserin is a nonhormonal, centrally acting molecule that acts as an agonist at postsynaptic 5-HT1A receptors and as an antagonist at 5-HT2A receptors. |
| M20299 | WAY-215718 | WAY-215718 is a 5-HT6 receptor antagonist. |
| M19276 | Rotundine | Rotundine is an antagonist of 5-HT1A with an IC50 of 370 nM. Rotundine is also an antagonist of dopamine D1, D2 and D3 receptors with IC50s of 166 nM, 1.4 μM and 3.3 μM, respectively. |
| M13880 | Tropisetron Hydrochloride | Tropisetron Hydrochloride (SDZ-ICS-930) is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor. |
| M13879 | Tropisetron | Tropisetron (SDZ-ICS-930 free base) is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor. |
| M13876 | SB-269970 hydrochloride | SB-269970 hydrochloride is a potent, selective and brain-penetrant 5-HT7 receptor antagonist with a pKi of 8.3. SB-269970 hydrochloride exhibits >50-fold selectivity against other 5-HT receptors. |
| M13875 | RU 24969 | RU 24969 is a preferential 5-HT1B agonist, with a Ki of 0.38 nM, but also displays appreciable affinity for the 5-HT1A receptor (Ki=2.5 nM), and has low affinity for other receptor sites in the brain. |
| M13872 | Ocaperidone | Ocaperidone is an effective antipsychotic agent, acting as a potent 5-HT2 and dopamine D2 antagonist, and a 5-HT1A agonist, with Kis of 0.14 nM, 0.46 nM, 0.75 nM, 1.6 nM and 5.4 nM for 5-HT2, a1-adrenergic receptor, dopamine D2, histamine H1 and a2-adrenergic receptor, respectively. |
| M13871 | Nelotanserin | Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively. |
| M13868 | Dihydroergotamine mesylate | Dihydroergotamine mesylate is an ergot alkaloid used to treat migraines. |
| M10779 | Alniditan dihydrochloride | Anidetam dihydrochloride Alniditan (Alnitidan) dihydrochloride is an effective one 5-HT1B and 5-HT1D RECEPTOR AGONISTS, IN HEK 293 CELLS, IN HUMANS 5-HT1B and people 5-HT1D receptors IC50 1.7 nM and 1.3 nM, respectively. Alniditan dihydrochloride has the effect of preventing migraines. |
| M8856 | WAY-100135 dihydrochloride | WAY-100135 dihydrochloride is a potent, selective 5-HT1A receptor antagonist (IC50 = 15 nM). |
| M8033 | Paroxetine hydrochloride hemihydrate | Paroxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI); antidepressant. |
| M8026 | Protriptyline hydrochloride | Norepinephrine uptake blocker. |
| M7767 | DOV 216,303 | DOV 216,303 is a potent triple inhibitor of 5-hydroxytryptamine (5-HT), norepinephrine, and dopamine reuptake with IC50 values of 20, 14, and 78 nM, respectively. |
| M7102 | Paroxetine maleate | Paroxetine maleate is a highly potent and selective 5-HT uptake inhibitor. |
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