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5-HT Receptor 5-hydroxytryptamine receptor

Cat.No.  Name Information
M14577 Fluoxetine Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research.
M5656 Fluoxetine hydrochloride Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
M3659 Pimavanserin Pimavanserin is a selective serotonin 5-HT2A inverse agonist, with pIC50 and pKd of 8.73 and 9.3, respectively.
M3417 Clozapine Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis.
M2821 Lorcaserin hydrochloride Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM.
M2048 Sumatriptan succinate Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache.
M58155 5-HT2B antagonist-1 5-HT2B antagonist-1 is an orally active 5-HT2B receptor antagonist with an IC50 value of 33.4 nM.
M55458 Aripiprazole-d8 Aripiprazole-d8
M55456 Clozapine-d8 Clozapine-d8
M55455 Olanzapine-d3 Olanzapine-d3
M55453 Quetiapine-d8 fumarate Quetiapine-d8 fumarate
M55451 Dapoxetine hydrochloride-d7 Dapoxetine hydrochloride-d7
M55445 Risperidone-d4 Risperidone-d4
M55224 Vabicaserin hydrochloride Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.
M45090 2-Methyl-5-hydroxytryptamine 2-Methyl-5-hydroxytryptamine is a potent, selective 5-HT3 receptor agonist that can be used in depression-related studies.
M40960 Gepirone Gepirone (Gepirone) is a first-in-class, selective, affinity-based, orally active 5-HT1A receptor partial agonist as well as a 5-HT2A receptor antagonist for use in studies related to anxiety, depression, and chronic kidney disease.
M31104 Strictosidinic acid Strictosidinic acid is an orally active glycoside indole monoterpene alkaloid, which inhibits precursor enzymes of 5-HT biosynthesis and reduces the 5-HT levels.
M30583 8-OH-DPAT hydrobromide 8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT1 binding site.
M30572 5-Carboxamidotryptamine maleate 5-Carboxamidotryptamine maleate (5-CT maleate) is a potent 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5 and 5-HT7 receptors agonist.
M30283 Cinanserin hydrochloride Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT2 receptor antagonist with a Ki of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT2 than for the 5-HT1 receptor (Ki of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.




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