| Cat.No. | Name | Information |
|---|---|---|
| M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
| M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
| M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
| M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist, with pIC50 and pKd of 8.73 and 9.3, respectively. |
| M3006 | Sertraline hydrochloride | Sertraline hydrochloride is a 5-HT antagonist with Ki of 13 nM. |
| M8091 | PF-04995274 | PF-04995274 is a potent partial agonist of serotonin 5HT4 receptor with Ki = 0. |
| M7763 | Diacylglycerol Kinase Inhibitor I | Diacylglycerol Kinase Inhibitor I (R 59-022) is an inhibitor of Diacylglycerol Kinase (DGK) and 5-HT Receptor with an IC50 value of 2.8 µM for DGK and inhibits the phosphorylation of OAG to OAPA.In addition, Diacylglycerol Kinase Inhibitor I also activates protein kinase C (PKC). In addition, Diacylglycerol Kinase Kinase Inhibitor I also activates protein kinase C (PKC). |
| M7684 | Clozapine N-oxide | Clozapine N-oxide (CNO) is a 5-HT2 serotonin receptor antagonist; major metabolite of clopazine that can be monitored by HPLC. |
| M7259 | SB 228357 | SB 228357 is a 5-HT 2C/2B antagonist/inverse agonist. |
| M7248 | SB 200646 hydrochloride | SB 200646 hydrochloride is a 5-HT 2C/2B antagonist. |
| M7226 | RS 67333 hydrochloride | RS 67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum. |
| M6984 | MM 77 dihydrochloride | MM 77 dihydrochloride is a 5-HT 1A (postsynaptic) antagonist. |
| M6946 | Melperone hydrochloride | Melperone hydrochloride is a 5-HT2A/D2 receptor antagonist; neuroleptic. |
| M6933 | LY334370 | LY 334370 is a selective 5-HT1F agonist. |
| M6760 | GR 127935 hydrochloride | GR 127935 hydrochloride is a potent, selective 5-HT 1B/1D antagonist. |
| M6759 | GR 113808 | GR 113808 is a potent, selective 5-HT 4 antagonist. |
| M6343 | 4F 4PP oxalate | 4F 4PP oxalate is a selective 5-HT 2A antagonist. |
| M6333 | 3-AQC | 3-AQC is a 5-HT 3 antagonist. |
| M6065 | Ziprasidone HCl monohydrate | Ziprasidone(CP88059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. |
| M6064 | Ziprasidone HCl | Ziprasidone HCl is a novel and potent dopamine and serotonin (5-HT) receptor antagonist, used in the treatment of schizophrenia and bipolar disorder. |
| M6058 | Vortioxetine | Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. |
| M6051 | Venlafaxine | Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. |
| M6050 | Venlafaxine HCl | Venlafaxine HCl is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia. |
| M6027 | Trazodone hydrochloride | Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders. |
| M5992 | Tegaserod maleate | Tegaserod maleate is a partial agonist of the 5-HT4 receptor; stimulates the peristaltic reflex and accelerates gastrointestinal transit. |
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