All AbMole products are for research use only, cannot be used for human consumption.

Sertraline hydrochloride is a 5-HT antagonist with Ki of 13 nM.
BioRxiv. 2024 Oct 04;616673.
Temperature-induced membrane trafficking drives antibody delivery to the brain
Sertraline hydrochloride purchased from AbMole
bioRxiv. 2024 Oct 08.
Temperature-induced membrane trafficking drives antibody delivery to the brain
Sertraline hydrochloride purchased from AbMole
| Cell Experiment | |
|---|---|
| Cell lines | |
| Preparation method | |
| Concentrations | |
| Incubation time | |
| Animal Experiment | |
|---|---|
| Animal models | Rats, Mice |
| Formulation | In water or the mixture (% by volume), 5% ethanol + 5% Emulphor-EL-620 + 90%normal saline. |
| Dosages | |
| Administration | i.p. |
| Molecular Weight | 342.69 |
| Formula | C17H17Cl2N.HCl |
| CAS Number | 79559-97-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage | 2-8°C |
[2] Andrea Cipriani, et al. Sertraline versus other antidepressive agents for depression
[4] C Lindsay DeVane, et al. Clinical pharmacokinetics of sertraline
| Related 5-HT Receptor Products |
|---|
| Vortioxetine hydrobromide
Vortioxetine hydrobromide (Lu AA21004) is a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist, a 5-HT1B receptor partial agonist, a 5-HT1A receptor agonist and a 5-HT transporter (5-HTT) inhibitor in vitro. |
| Prucalopride
Prucalopride is a potent, selective and specific serotonin 5-HT4 receptor agonist with enterokinetic properties. |
| (1S-cis)-Milnacipran Hydrochloride
(1S-cis)-Milnacipran hydrochloride is a selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. |
| Latrepirdine dihydrochloride
Latrepirdine dihydrochloride is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion. |
| Mianserin hydrochloride
Mianserin HCl is a tetracyclic antidepressant compound. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.