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Sertraline hydrochloride is a 5-HT antagonist with Ki of 13 nM.
bioRxiv. 2024 Oct 08.
Temperature-induced membrane trafficking drives antibody delivery to the brain
Sertraline hydrochloride purchased from AbMole
| Cell Experiment | |
|---|---|
| Cell lines | |
| Preparation method | |
| Concentrations | |
| Incubation time | |
| Animal Experiment | |
|---|---|
| Animal models | Rats, Mice |
| Formulation | In water or the mixture (% by volume), 5% ethanol + 5% Emulphor-EL-620 + 90%normal saline. |
| Dosages | |
| Administration | i.p. |
| Molecular Weight | 342.69 |
| Formula | C17H17Cl2N.HCl |
| CAS Number | 79559-97-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage | 2-8°C |
[3] Andrea Cipriani, et al. Sertraline versus other antidepressive agents for depression
[5] C Lindsay DeVane, et al. Clinical pharmacokinetics of sertraline
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| GR127935
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