| Cat.No. | Name | Information |
|---|---|---|
| M2048 | Sumatriptan succinate | Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| M3417 | Clozapine | Clozapine is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis. |
| M2821 | Lorcaserin hydrochloride | Lorcaserin hydrochloride is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM. |
| M5656 | Fluoxetine hydrochloride | Fluoxetine hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| M14577 | Fluoxetine | Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research. |
| M3659 | Pimavanserin | Pimavanserin is a selective serotonin 5-HT2A inverse agonist. |
| M5798 | Mosapride | Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist. |
| M5754 | Loxapine | Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent. |
| M5660 | Fluvoxamine maleate | Fluvoxamine Maleate is a selective serotonin (5-HT) reuptake inhibitor (SSRI), used in the treatment of obsessive-compulsive disorder. |
| M5601 | Duloxetine HCl | Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). |
| M5548 | Dalasetron Mesylate hydrate | Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. |
| M5543 | Cyproheptadine hydrochloride sesquihydrate | Cyproheptadine hydrochloride sesquihydrate is an antihistamine and is an antagonist of serotonin and histamine2. |
| M5542 | Cyproheptadine HCl | Cyproheptadine is a histamine receptor antagonist for 5-HT2 receptor with IC50 of 0.6 nM. |
| M5475 | Cabergoline | Cabergoline, an ergot derivative, is a potent dopamine receptor agonist on D2 receptors. |
| M5466 | Blonanserin | Blonanserin is a relatively selective serotonin (5-HT)2A and dopamine D2 antagonist, used the treatment of schizophrenia. |
| M5424 | Asenapine maleate | Asenapine maleate is a high-affinity antagonist of various receptors including serotonin receptors (5-HT), norepinephrine (NA), dopamine receptors, and histamine receptors, and can be used in studies related to neurodivergent disorders as well as depressive manic depression. |
| M5423 | Asenapine | Asenapine(Org 5222) inhibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM. |
| M5400 | Alosetron Hydrochloride | Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. |
| M5369 | Fenclonine (4-Chloro-DL-phenylalanine) | Fenclonine (4-Chloro-DL-phenylalanine) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine (4-Chloro-DL-phenylalanine) acts pharmacologically to deplete endogenous levels of serotonin. |
| M5214 | Lasmiditan hydrochloride | Lasmiditan hydrochloride (also known as COL-144 and LY573144) is a high-affinity, highly selective serotonin (5-HT) 5-HT(1F) receptor agonist. |
| M5134 | WAY-181187 | Way-181187 (SAX-187) is an effective selective 5-HT6 receptor agonist with Ki of 2.2 nM and EC50 of 6.6 nM. WAY181187 mediates 5-HT6 receptor-dependent signaling pathways, such as cAMP, Fyn and ERK1/2 kinases, as specific agonists. |
| M5130 | Cisapride | Cisapride(R 51619) is a nonselective 5-HT4 receptor agonist, it is also a potent hERG potassium channel inhibitor. IC50 Value is 0.14 μM (EC50 for 5-HT4 receptor). |
| M5045 | Tianeptine | Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo. |
| M5044 | Tianeptine sodium salt | Tianeptine sodium salt is a selective facilitator of 5-HT uptake in vitro and in vivo. |
| M5033 | Escitalopram | Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with Ki of 0.89 nM. |
| M5022 | Almotriptan Malate | Almotriptan Malate is a 5-HT1B/1D-receptor agonist used for the research of migraine. |
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