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NPS ALX Compound 4a dihydrochloride

Cat. No. M7043

All AbMole products are for research use only, cannot be used for human consumption.

NPS ALX Compound 4a dihydrochloride Structure

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Quality Control & Documentation
Biological Activity

NPS ALX Compound 4a dihydrochloride is a potent and competitive 5-HT6 antagonist (IC50 = 7.2 nM, Ki = 0.2 nM) that displays selectivity over other 5-HT and D2 receptors.

Chemical Information
Molecular Weight 504.47
Formula C25H25N3O2S.2HCl
CAS Number 299433-10-6
Solubility (25°C) DMSO 50.45 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Fish, et al. J Med Chem. Identification of a chemical probe for bromo and extra c-terminal bromodomain inhibition through optimization of a fragment-derived hit.

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