| Cat.No. | Name | Information |
|---|---|---|
| M2849 | Microcystin-LR | Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1. |
| M6314 | SHP099 | SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM. |
| M7533 | SHP099 hydrochloride | SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM. |
| M6300 | (-)-p-Bromotetramisole Oxalate | (-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor. |
| M5967 | Sodium Fluoride | Sodium Fluoride is an inorganic salt of fluoride, used as an insecticide. It is also used to fluorinate water supplies, as a wood preservative, in cleaning compounds, manufacture of glass, and for many other uses. |
| M5195 | Okadaic acid | Okadaic acid is a potent inhibitor of protein phosphatase 1/2A with IC50 values of 19 nM and 0.2 nM for protein phosphatase 1 and protein phosphatase 2A, respectively. |
| M5102 | PTP1B-IN-2 | PTP1B-IN-2 is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM. |
| M4596 | Silydianin | Silydianin, the active ingredient of silythistle, has anti-collagenase and anti-elastic enzyme activities. Silydianin is a natural protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 17.38 μM. Silydianin inhibited the production and release of oxidation products in vitro. |
| M4324 | Rhein-8-O-β-D-glucopyranoside | Rhein-8-glucoside calcium, a anthraquinone compound isolated from EtOH extract of Saussurea lappa root. Rhein-8-glucoside calcium is an hPTP1B inhibitor with an IC50 value of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects. |
| M3837 | β-Glycerophosphate disodium salt hydrate | β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. |
| M2993 | Sal003 | Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor. |
| M2499 | CCT007093 | CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM. |
| M54818 | M5N36 | M5N36 is a potent and selective Cdc25C inhibitor with IC50 values of 0.15, 0.19, 0.06 µM for Cdc25A, Cdc25B, Cdc25C, respectively. |
| M54807 | DPM-1003 | DPM-1003 is an orally potent, specific inhibitor of PTP1B. |
| M54137 | D-3 | D-3, a phosphorpeptide, is an efficient, simple, and specific iPSC-eliminating agent. |
| M54117 | EGF Receptor Substrate 2 (Phospho-Tyr5) | EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. |
| M54029 | Calcineurin autoinhibitory peptide | Calcineurin autoinhibitory peptide is a selective inhibitor of Ca2+/calmodulin-dependent protein phosphatase (calcineurin), with an IC50 of ~10 μM. |
| M52555 | [pTyr5] EGFR (988-993) | [pTyr5] EGFR (988-993) is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). |
| M52554 | Microcystin-LA | Microcystin LA, a natural toxin, exerts its cytotoxic exects by inhibiting the serine-threonine protein phosphatases PP1 and PP2A with IC50s of 0.3 and 0.3 nM, respectively. |
| M52553 | Cyclosporin A-Derivative 3 | Cyclosporin A-Derivative 3 is a derivative of Cyclosporin A with calcineurin inhibition. |
| M52552 | Microcystin-RR | Microcystin-RR (Cyanoviridin RR) is a potent and orally active protein phosphatase inhibitor. |
| M52551 | 11R-CaN-AID | 11R-CaN-AID is a potent and cell permeant inhibitor of calcineurin. |
| M49784 | SHP2-IN-23 | SHP2-IN-23 is an orally active SHP2 inhibitor (IC50=38 nM) with excellent in vivo efficacy and pharmacokinetic profiles. |
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