Phosphatase Phosphatase

Cat.No.	Name	Information
M2849	Microcystin-LR	Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
M6314	SHP099	SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM.
M7533	SHP099 hydrochloride	SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM.
M14493	MSI-1436 lactate	MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM).
M3837	β-Glycerophosphate disodium salt hydrate	β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.
M10278	Raphin1	Raphin1 is an orally bioavailable, selective R15B (PPP1R15B, a regulatory subunit of protein phosphatase 1) inhibitor, strongly binding to the R15B-PP1c holophosphatase with Kd of 33 nM.
M10027	C2 Ceramide	C2 Ceramide (N-Acetyl-D-sphingosine) is a cell-permeable and biologically active ceramide, it induces differentiation and apoptosis in cells and has been shown to activate protein phosphatases.
M9948	SC-43	SC-43 is a sorafenib derivative, it is a potent and orally active SHP-1 (PTPN6) agonist with anti-tumor activity.
M9898	TNO155	TNO155 is a first-in-class, selective, orally active wild-type SHP2 metamorphosis inhibitor with an IC50 value of 0.011 µM. tNO155 has good water solubility (0.736 mM), moderate lipophilicity (LogP=1.6), high lipophilic efficiency (>6), and no hERG inhibition (IC50 >30 μM) and no phototoxicity. Does not inhibit CYP450.
M9699	KY-226	KY-226 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with IC50 of 0.25 μM, which protects neurons from cerebral ischemic injury.
M9518	BN82002	BN82002, also known as CDC25 Phosphatase Inhibitor I, is a potent, selective, and irreversible inhibitor of CDC25 phosphatase family (IC50 = 2.4, 3.9, 6.3, 5.4, and 4.6 µM for 25A, 25B2, 25B3, 25C, and 25C-cat, respectively).
M9513	BTdCPU	BTdCPU is an potent activator of HRI, it promotes eIF2α phosphorylation and induced apoptosis in resistant cell.
M9467	F1063-0967	F1063-0967 is a novel inhibitor of dual-specificity phosphatase 26 (DUSP26), inducing apoptosis in IMR-32 cell line.
M9403	TPI-1	TPI-1 is a SHP-1 inhibitor, inhibits recombinant SHP-1 with an IC50 of 40 nM.
M9231	RMC-4550	RMC-4550 is a potent and selective SHP2 inhibitor, with an IC50 of 0.583 nM.
M9081	Sodium Stibogluconate	Sodium Stibogluconate is a potent inhibitor of protein tyrosine phosphatase.
M8760	KLH45	KLH45 is an in vivo-active, potent and selective irreversible inhibitor of DDHD2.
M7060	NSC 95397	NSC 95397 is a selective Cdc25 dual specificity phosphatase inhibitor.
M7059	NSC-87877	Nsc-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatase with IC50 values of 0.318 μM and 0.355 μM, respectively. Nsc-87877 also inhibits bispecific phosphatase 26 (DUSP26).
M6881	L-690,330	L-690,330 is a inositol monophosphatase inhibitor.
M6770	GSK 2830371	GSK 2830371 is a potent and selective allosteric inhibitor of Wip1 phosphatase.
M6300	(-)-p-Bromotetramisole Oxalate	(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.
M5967	Sodium Fluoride	Sodium Fluoride is an inorganic salt of fluoride, used as an insecticide. It is also used to fluorinate water supplies, as a wood preservative, in cleaning compounds, manufacture of glass, and for many other uses.
M5195	Okadaic acid	Okadaic acid is a potent inhibitor of protein phosphatase 1/2A with IC50 values of 19 nM and 0.2 nM for protein phosphatase 1 and protein phosphatase 2A, respectively.
M5102	PTP1B-IN-2	PTP1B-IN-2 is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM.

By Signaling Pathways

By Product Type

Signaling Pathways

Phosphatase Phosphatase

Get to Know Us

Customer Support

Resources

Contact Us