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Phosphatase Phosphatase

Cat.No.  Name Information
M2849 Microcystin-LR Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
M6314 SHP099 SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM.
M7533 SHP099 hydrochloride SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM.
M9513 BTdCPU BTdCPU is an potent activator of HRI, it promotes eIF2α phosphorylation and induced apoptosis in resistant cell.
M9467 F1063-0967 F1063-0967 is a novel inhibitor of dual-specificity phosphatase 26 (DUSP26), inducing apoptosis in IMR-32 cell line.
M9403 TPI-1 TPI-1 is a SHP-1 inhibitor, inhibits recombinant SHP-1 with an IC50 of 40 nM.
M9231 RMC-4550 RMC-4550 is a potent and selective SHP2 inhibitor, with an IC50 of 0.583 nM.
M9081 Sodium Stibogluconate Sodium Stibogluconate is a potent inhibitor of protein tyrosine phosphatase.
M8760 KLH45 KLH45 is an in vivo-active, potent and selective irreversible inhibitor of DDHD2.
M7060 NSC 95397 NSC 95397 is a selective Cdc25 dual specificity phosphatase inhibitor.
M7059 NSC-87877 Nsc-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatase with IC50 values of 0.318 μM and 0.355 μM, respectively. Nsc-87877 also inhibits bispecific phosphatase 26 (DUSP26).
M6881 L-690,330 L-690,330 is a inositol monophosphatase inhibitor.
M6770 GSK 2830371 GSK 2830371 is a potent and selective allosteric inhibitor of Wip1 phosphatase.
M6300 (-)-p-Bromotetramisole Oxalate (-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.
M5967 Sodium Fluoride Sodium Fluoride is an inorganic salt of fluoride, used as an insecticide. It is also used to fluorinate water supplies, as a wood preservative, in cleaning compounds, manufacture of glass, and for many other uses.
M5195 Okadaic acid Okadaic acid is a potent inhibitor of protein phosphatase 1/2A with IC50 values of 19 nM and 0.2 nM for protein phosphatase 1 and protein phosphatase 2A, respectively.
M5102 PTP1B-IN-2 PTP1B-IN-2 is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM.
M4596 Silydianin Silydianin, the active ingredient of silythistle, has anti-collagenase and anti-elastic enzyme activities. Silydianin is a natural protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 17.38 μM. Silydianin inhibited the production and release of oxidation products in vitro.
M4324 Rhein-8-O-β-D-glucopyranoside Rhein-8-glucoside calcium, a anthraquinone compound isolated from EtOH extract of Saussurea lappa root. Rhein-8-glucoside calcium is an hPTP1B inhibitor with an IC50 value of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects.
M3837 β-Glycerophosphate disodium salt hydrate β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.
M2993 Sal003 Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor.
M2499 CCT007093 CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM.
M57214 RMC-3943  RMC-3943 is an allosteric SHP2 inhibitor (inhibition of full-length SHP2 in biochemical assay, IC50 = 2.19 nM).




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