| Cat.No. | Name | Information |
|---|---|---|
| M2849 | Microcystin-LR | Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1. |
| M6314 | SHP099 | SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM. |
| M7533 | SHP099 hydrochloride | SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM. |
| M9231 | RMC-4550 | RMC-4550 is a potent and selective SHP2 inhibitor, with an IC50 of 0.583 nM. |
| M9081 | Sodium Stibogluconate | Sodium Stibogluconate is a potent inhibitor of protein tyrosine phosphatase. |
| M8760 | KLH45 | KLH45 is an in vivo-active, potent and selective irreversible inhibitor of DDHD2. |
| M7060 | NSC 95397 | NSC 95397 is a selective Cdc25 dual specificity phosphatase inhibitor. |
| M7059 | NSC-87877 | Nsc-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatase with IC50 values of 0.318 μM and 0.355 μM, respectively. Nsc-87877 also inhibits bispecific phosphatase 26 (DUSP26). |
| M6881 | L-690,330 | L-690,330 is a inositol monophosphatase inhibitor. |
| M6770 | GSK 2830371 | GSK 2830371 is a potent and selective allosteric inhibitor of Wip1 phosphatase. |
| M6300 | (-)-p-Bromotetramisole Oxalate | (-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor. |
| M5195 | Okadaic acid | Okadaic acid is a potent inhibitor of protein phosphatase 1/2A with IC50 values of 19 nM and 0.2 nM for protein phosphatase 1 and protein phosphatase 2A, respectively. |
| M5102 | PTP1B-IN-2 | PTP1B-IN-2 is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM. |
| M4596 | Silydianin | Silydianin, the active ingredient of silythistle, has anti-collagenase and anti-elastic enzyme activities. Silydianin is a natural protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 17.38 μM. Silydianin inhibited the production and release of oxidation products in vitro. |
| M4324 | Rhein-8-O-β-D-glucopyranoside | Rhein-8-glucoside calcium, a anthraquinone compound isolated from EtOH extract of Saussurea lappa root. Rhein-8-glucoside calcium is an hPTP1B inhibitor with an IC50 value of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects. |
| M3837 | β-Glycerophosphate disodium salt hydrate | β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. |
| M2993 | Sal003 | Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor. |
| M2499 | CCT007093 | CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM. |
| M57214 | RMC-3943 | RMC-3943 is an allosteric SHP2 inhibitor (inhibition of full-length SHP2 in biochemical assay, IC50 = 2.19 nM). |
| M57213 | LYP-IN-1 | LYP-IN-1 is a potent, selective and specific LYP inhibitor with a Ki and an IC50 of 110 nM and 0.259 μM, respectively. |
| M57212 | PF-07284892 | PF-07284892 (ARRY-558) is a potent and orally active SHP2 inhibitor with an IC50 value of 21 nM. |
| M56750 | MY10 | MY10 is a potent and orally active receptor protein tyrosine phosphatase (RPTPβ/ζ) inhibitor. |
| M56749 | CPDA | CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor. |
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