Cat.No. | Name | Information |
---|---|---|
M2849 | Microcystin-LR | Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1. |
M6314 | SHP099 | SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM. |
M7533 | SHP099 hydrochloride | SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM. |
M14488 | DIPQUO | DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β. |
M14486 | BN82002 hydrochloride | BN82002 hydrochloride is a potent, selective and irreversible inhibitor of CDC25 phosphatase family. |
M14485 | BCI | BCI is an allosteric inhibitor of dual specificity phosphatase (DUSP). BCI specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI does not inhibit DUSP5. |
M14484 | ARL67156 trisodium salt hydrate | ARL67156 trisodium salt hydrate is an inhibitor of ecto-ATPase. |
M14483 | ARL67156 trisodium salt | ARL67156 trisodium salt is an inhibitor of ecto-ATPase. |
M14482 | Aloe-emodin-8-O-β-D-glucopyranoside | Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC50 of 26.6 μM. |
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