Phosphatase Phosphatase

Cat.No.	Name	Information
M2849	Microcystin-LR	Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
M6314	SHP099	SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM.
M7533	SHP099 hydrochloride	SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM.
M42550	PTPN2/1-IN-2	PTPN2/1-IN-2 is a PTPN2/1 antagonist that can be used in various tumor research.
M42549	PTP1B/AKR1B1-IN-2	PTP1B/AKR1B1-IN-2 is a dual PTP1B/AKR1B1 inhibitor (IC50s: 3.2 and 2.1 μM, Kis: 4.0 and 0.9μM).
M42548	h-NTPDase8-IN-1	h-NTPDase8-IN-1 is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM).
M42547	cis-Ferulic acid 4-O-β-D-glucopyranoside	cis-Ferulic acid 4-O-β-D-glucopyranoside is a phenolic glycosid, which can be isolated from Nitraria sibirica..
M42546	LYP-IN-4	LYP-IN-4 is a reversible and selective inhibitor of lymphotyrosine phosphatase (LYP) (Ki=1.34 μM, IC50=3.52μM).
M42545	h-NTPDase-IN-1	h-NTPDase-IN-1 is a h-NTPDase inhibitor (IC50: 2.88 μM and 0.72 μM for h-NTPDase1 and h-NTPDase3 respectively).
M42544	NC1	NC1 is a noncompetitive and allosteric lymphoid-specific tyrosine phosphatase (LYP) inhibitor, with a Ki value 4.3 μM.
M42543	PROTAC PTPN2 degrader-2	PROTAC PTPN2 degrader-2 is a potent PTPN2 degrader with potential for studying cancer or metabolic diseases.
M42542	PROTAC PTPN2 degrader-2 TFA	PROTAC PTPN2 degrader-2 TFA is a potent PTPN2 degrader with potential for studying cancer or metabolic diseases.
M42541	Tegeprotafib	Tegeprotafib (PTPN2/1-IN-1) is an orally active PTPN1 and PTPN2 inhibitor with IC50s of 4.4 nM and 1-10 nM against PTPN2 and PTP1B, respectively.
M42540	h-NTPDase-IN-5	h-NTPDase-IN-5 is a pan-inhibitor of NTPDase with IC50s of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), 0.32 μM (h- NTPDase8).
M42539	h-NTPDase-IN-4	h-NTPDase-IN-4 is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).
M42538	h-NTPDase-IN-3	h-NTPDase-IN-3 is a pan-inhibitor of NTPDase with IC50s of 34.13 μM (h-NTPDase1), 0.33 μM (h-NTPDase2), 23.21 μM (h-NTPDase3), 2.48 μM (h- NTPDase8).
M42537	LYP-IN-3	LYP-IN-3 is a selective inhibitor of Lymphoid-tyrosine phosphatase (LYP) (Ki=0.93 μM), and regulates T-cell receptor (TCR) signaling pathway in tumor progress.
M42536	PTP1B/AKR1B1-IN-1	PTP1B/AKR1B1-IN-1 is a dual inhibitor of protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), with IC50s of 0.06 μM and 4.3 μM, respectively.
M42535	h-NTPDase-IN-2	h-NTPDase-IN-2 is a pan-inhibitor of h-NTPDase, with IC50s of 0.35 μM (h-NTPDase1), 4.81 μM (h-NTPDase2), 37.73 μM (h-NTPDase3), 10.32 μM (h-NTPDase8), respectively.
M39167	Uralsaponin D	Uralsaponin D is a saponin that can be isolated from Glycyrrhiza inflata. Uralsaponin D inhibits phospholipase A2 (PLA2) with an IC50 value of 32.2 μM.
M39166	Momordicoside A	Momordicoside A is isolated from Momordica charantia L. Momordicoside A has the inhibitory effect on protein tyrosine phosphatase (PTP1B).
M39165	2-Hydroxymethyl-3-hydroxyanthraquinone	2-Hydroxymethyl-3-hydroxyanthraquinone is an antiosteoporotic compound that inhibits osteoclastic tartrate-resistant acid phosphatase (TRAP) activity.
M39163	1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)	1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl) shows in vitro inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 13.00 μM. PTP1B is a negative regulator of insulin action and an important mediator in the pathogenesis of insulinresistance and non-insulin dependent diabetes mellitus.

By Signaling Pathways

By Product Type

Signaling Pathways

Phosphatase Phosphatase

Get to Know Us

Customer Support

Resources

Contact Us