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Phosphatase Phosphatase

Cat.No.  Name Information
M2849 Microcystin-LR Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
M6314 SHP099 SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM.
M7533 SHP099 hydrochloride SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM.
M14493 MSI-1436 lactate MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM).
M3837 β-Glycerophosphate disodium salt hydrate β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.
M43526 SHP2-IN-14 SHP2-IN-14 is an orally active and potent SHP2 allosteric inhibitor (IC50=7 nM) with anti-tumor activity.
M43525 SHP2-IN-13 SHP2-IN-13 is a highly selective and orally active SHP2 “tunnel site” allosteric inhibitor with an IC50 of 83.0 nM.
M42553 ITH12711 ITH12711 is a PP2A ligand.
M42552 Orellanine Orellanine is a fungal nephrotoxin.
M42551 Phosphatase-IN-1 Phosphatase-IN-1 derivative, is a phosphatidate phosphatase (Pah) inhibitor.
M42550 PTPN2/1-IN-2 PTPN2/1-IN-2 is a PTPN2/1 antagonist that can be used in various tumor research.
M42549 PTP1B/AKR1B1-IN-2 PTP1B/AKR1B1-IN-2 is a dual PTP1B/AKR1B1 inhibitor (IC50s: 3.2 and 2.1 μM, Kis: 4.0 and 0.9μM).
M42548 h-NTPDase8-IN-1 h-NTPDase8-IN-1 is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM).
M42547 cis-Ferulic acid 4-O-β-D-glucopyranoside cis-Ferulic acid 4-O-β-D-glucopyranoside is a phenolic glycosid, which can be isolated from Nitraria sibirica..
M42546 LYP-IN-4 LYP-IN-4 is a reversible and selective inhibitor of lymphotyrosine phosphatase (LYP) (Ki=1.34 μM, IC50=3.52μM).
M42545 h-NTPDase-IN-1 h-NTPDase-IN-1 is a h-NTPDase inhibitor (IC50: 2.88 μM and 0.72 μM for h-NTPDase1 and h-NTPDase3 respectively).
M42544 NC1 NC1 is a noncompetitive and allosteric lymphoid-specific tyrosine phosphatase (LYP) inhibitor, with a Ki value 4.3 μM.
M42543 PROTAC PTPN2 degrader-2 PROTAC PTPN2 degrader-2 is a potent PTPN2 degrader with potential for studying cancer or metabolic diseases.
M42542 PROTAC PTPN2 degrader-2 TFA PROTAC PTPN2 degrader-2 TFA is a potent PTPN2 degrader with potential for studying cancer or metabolic diseases.
M42541 Tegeprotafib Tegeprotafib (PTPN2/1-IN-1) is an orally active PTPN1 and PTPN2 inhibitor with IC50s of 4.4 nM and 1-10 nM against PTPN2 and PTP1B, respectively.
M42540 h-NTPDase-IN-5 h-NTPDase-IN-5 is a pan-inhibitor of NTPDase with IC50s of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), 0.32 μM (h- NTPDase8).
M42539 h-NTPDase-IN-4 h-NTPDase-IN-4 is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).
M42538 h-NTPDase-IN-3 h-NTPDase-IN-3 is a pan-inhibitor of NTPDase with IC50s of 34.13 μM (h-NTPDase1), 0.33 μM (h-NTPDase2), 23.21 μM (h-NTPDase3), 2.48 μM (h- NTPDase8).
M42537 LYP-IN-3 LYP-IN-3 is a selective inhibitor of Lymphoid-tyrosine phosphatase (LYP) (Ki=0.93 μM), and regulates T-cell receptor (TCR) signaling pathway in tumor progress.
M42536 PTP1B/AKR1B1-IN-1 PTP1B/AKR1B1-IN-1 is a dual inhibitor of protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), with IC50s of 0.06 μM and 4.3 μM, respectively.




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