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Phosphatase Phosphatase

Cat.No.  Name Information
M2849 Microcystin-LR Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
M6314 SHP099 SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM.
M7533 SHP099 hydrochloride SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM.
M57214 RMC-3943  RMC-3943 is an allosteric SHP2 inhibitor (inhibition of full-length SHP2 in biochemical assay, IC50 = 2.19 nM).
M57213 LYP-IN-1  LYP-IN-1 is a potent, selective and specific LYP inhibitor with a Ki and an IC50 of 110 nM and 0.259 μM, respectively.
M57212 PF-07284892 PF-07284892 (ARRY-558) is a potent and orally active SHP2 inhibitor with an IC50 value of 21 nM.
M56750 MY10  MY10 is a potent and orally active receptor protein tyrosine phosphatase (RPTPβ/ζ) inhibitor.
M56749 CPDA  CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor.
M56748 HKB99  HKB99 is an allosteric inhibitor of phosphoglycerate mutase 1 (PGAM1).
M56747 7-BIA  7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with an IC50 of ~1-3 μM.
M56746 MY33-3  MY33-3 is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM.
M56745 CX08005  CX08005 is a competitive PTP1B inhibitor.
M56744 ARL67156 ARL67156 is an inhibitor of ecto-ATPase.
M56743 PTP1B-IN-3  PTP1B-IN-3 is a potent and orally active PTP1B inhibitor with IC50s of 120 nM for both PTP1B and TCPTP.
M56742 PPM1A-IN-1  PPM1A-IN-1 is an inhibitor for PP2C Ser/Thr phosphatase protein phosphatase Mg2+/Mn2+-dependent 1A.
M56741 (Rac)-RK-682  (Rac)-RK-682, a racemate of RK-682, is a protein tyrosine phosphatases (PTPases) inhibitor.
M56740 PTP1B-IN-15  PTP1B-IN-15 is a potent and selective inhibitor of protein tyrosine phosphatase 1B (PTP1B).
M56739 5-FAM-Alkyne  5-FAM-Alkyne is a high selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP).
M56738 Naphthol AS-BR  Naphthol AS-BR is a substrate for the histochemical demonstration of acid and alkaline phosphatase.
M56737 PTP Inhibitor IV  PTP Inhibitor IV is a protein tyrosine phosphatase (PTP) inhibitor that competitively inhibits DUSP14 phosphatase activity with an 50 of 5.21 μM.
M56736 MY33-3 hydrochloride  MY33-3 hydrochloride is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM.
M56735 (R)-Azasetron besylate (R)-Azasetron besylate (SENS-401) is an orally active calcineurin inhibitor.
M56734 PTP1B-IN-3 diammonium  PTP1B-IN-3 diammonium is a potent and orally active PTP1B inhibitor with IC50s of 120 nM for both PTP1B and TCPTP.




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