| Cat.No. | Name | Information |
|---|---|---|
| M2849 | Microcystin-LR | Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1. |
| M6314 | SHP099 | SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM. |
| M7533 | SHP099 hydrochloride | SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM. |
| M45095 | 5MPN | 5MPN is a first-in-class, orally active and selective inhibitor of fructose-6-phosphate-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4), which does not inhibit PFK-1 or PFKFB3. 5MPN is a competitive inhibitor of the F6P-binding site (Ki=8.6 μM). 5MPN inhibits proliferation of various cancer cell lines by targeting tumor glucose metabolism. 5MPN is a competitive inhibitor of the F6P binding site (Ki=8.6 μM). 5MPN can inhibit the proliferation of various cancer cell lines by targeting tumor glycolysis. |
| M45015 | Tartaric acid disodium dihydrate | Tartaric acid disodium dihydrate is a Acid phosphatase inhibitor, is a sodium salt used in buffers for molecular biology and cell culture applications. Tartaric acid disodium dihydrate increases the rate of colchicine binding to tubulin1. |
| M43528 | YF704 | YF704 is a selective allosteric inhibitor of SHP2 (IC50=0.25 μM). |
| M43527 | CNBCA | CNBCA is a potent, selective, competitive SHP2 enzyme inhibitor, with the IC50 of 0.87 μM. |
| M43526 | SHP2-IN-14 | SHP2-IN-14 is an orally active and potent SHP2 allosteric inhibitor (IC50=7 nM) with anti-tumor activity. |
| M43525 | SHP2-IN-13 | SHP2-IN-13 is a highly selective and orally active SHP2 “tunnel site” allosteric inhibitor with an IC50 of 83.0 nM. |
| M42553 | ITH12711 | ITH12711 is a PP2A ligand. |
| M42552 | Orellanine | Orellanine is a fungal nephrotoxin. |
| M42551 | Phosphatase-IN-1 | Phosphatase-IN-1 derivative, is a phosphatidate phosphatase (Pah) inhibitor. |
| M42550 | PTPN2/1-IN-2 | PTPN2/1-IN-2 is a PTPN2/1 antagonist that can be used in various tumor research. |
| M42549 | PTP1B/AKR1B1-IN-2 | PTP1B/AKR1B1-IN-2 is a dual PTP1B/AKR1B1 inhibitor (IC50s: 3.2 and 2.1 μM, Kis: 4.0 and 0.9μM). |
| M42548 | h-NTPDase8-IN-1 | h-NTPDase8-IN-1 is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). |
| M42547 | cis-Ferulic acid 4-O-β-D-glucopyranoside | cis-Ferulic acid 4-O-β-D-glucopyranoside is a phenolic glycosid, which can be isolated from Nitraria sibirica.. |
| M42546 | LYP-IN-4 | LYP-IN-4 is a reversible and selective inhibitor of lymphotyrosine phosphatase (LYP) (Ki=1.34 μM, IC50=3.52μM). |
| M42545 | h-NTPDase-IN-1 | h-NTPDase-IN-1 is a h-NTPDase inhibitor (IC50: 2.88 μM and 0.72 μM for h-NTPDase1 and h-NTPDase3 respectively). |
| M42544 | NC1 | NC1 is a noncompetitive and allosteric lymphoid-specific tyrosine phosphatase (LYP) inhibitor, with a Ki value 4.3 μM. |
| M42543 | PROTAC PTPN2 degrader-2 | PROTAC PTPN2 degrader-2 is a potent PTPN2 degrader with potential for studying cancer or metabolic diseases. |
| M42542 | PROTAC PTPN2 degrader-2 TFA | PROTAC PTPN2 degrader-2 TFA is a potent PTPN2 degrader with potential for studying cancer or metabolic diseases. |
| M42541 | Tegeprotafib | Tegeprotafib (PTPN2/1-IN-1) is an orally active PTPN1 and PTPN2 inhibitor with IC50s of 4.4 nM and 1-10 nM against PTPN2 and PTP1B, respectively. |
| M42540 | h-NTPDase-IN-5 | h-NTPDase-IN-5 is a pan-inhibitor of NTPDase with IC50s of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), 0.32 μM (h- NTPDase8). |
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