| Cat.No. | Name | Information |
|---|---|---|
| M2849 | Microcystin-LR | Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1. |
| M6314 | SHP099 | SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM. |
| M7533 | SHP099 hydrochloride | SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM. |
| M14493 | MSI-1436 lactate | MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM). |
| M3837 | β-Glycerophosphate disodium salt hydrate | β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. |
| M56737 | PTP Inhibitor IV | PTP Inhibitor IV is a protein tyrosine phosphatase (PTP) inhibitor that competitively inhibits DUSP14 phosphatase activity with an 50 of 5.21 μM. |
| M56736 | MY33-3 hydrochloride | MY33-3 hydrochloride is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM. |
| M56735 | (R)-Azasetron besylate | (R)-Azasetron besylate (SENS-401) is an orally active calcineurin inhibitor. |
| M56734 | PTP1B-IN-3 diammonium | PTP1B-IN-3 diammonium is a potent and orally active PTP1B inhibitor with IC50s of 120 nM for both PTP1B and TCPTP. |
| M56733 | Icerguastat Carbonate | Icerguastat (Sephin1) Carbonate, a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). |
| M54818 | M5N36 | M5N36 is a potent and selective Cdc25C inhibitor with IC50 values of 0.15, 0.19, 0.06 µM for Cdc25A, Cdc25B, Cdc25C, respectively. |
| M54807 | DPM-1003 | DPM-1003 is an orally potent, specific inhibitor of PTP1B. |
| M54137 | D-3 | D-3, a phosphorpeptide, is an efficient, simple, and specific iPSC-eliminating agent. |
| M54117 | EGF Receptor Substrate 2 (Phospho-Tyr5) | EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. |
| M54029 | Calcineurin autoinhibitory peptide | Calcineurin autoinhibitory peptide is a selective inhibitor of Ca2+/calmodulin-dependent protein phosphatase (calcineurin), with an IC50 of ~10 μM. |
| M52555 | [pTyr5] EGFR (988-993) | [pTyr5] EGFR (988-993) is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). |
| M52554 | Microcystin-LA | Microcystin LA, a natural toxin, exerts its cytotoxic exects by inhibiting the serine-threonine protein phosphatases PP1 and PP2A with IC50s of 0.3 and 0.3 nM, respectively. |
| M52553 | Cyclosporin A-Derivative 3 | Cyclosporin A-Derivative 3 is a derivative of Cyclosporin A with calcineurin inhibition. |
| M52552 | Microcystin-RR | Microcystin-RR (Cyanoviridin RR) is a potent and orally active protein phosphatase inhibitor. |
| M52551 | 11R-CaN-AID | 11R-CaN-AID is a potent and cell permeant inhibitor of calcineurin. |
| M49784 | SHP2-IN-23 | SHP2-IN-23 is an orally active SHP2 inhibitor (IC50=38 nM) with excellent in vivo efficacy and pharmacokinetic profiles. |
| M45095 | 5MPN | 5MPN is a first-in-class, orally active and selective inhibitor of fructose-6-phosphate-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4), which does not inhibit PFK-1 or PFKFB3. 5MPN is a competitive inhibitor of the F6P-binding site (Ki=8.6 μM). 5MPN inhibits proliferation of various cancer cell lines by targeting tumor glucose metabolism. 5MPN is a competitive inhibitor of the F6P binding site (Ki=8.6 μM). 5MPN can inhibit the proliferation of various cancer cell lines by targeting tumor glycolysis. |
| M45015 | Tartaric acid disodium dihydrate | Tartaric acid disodium dihydrate is a Acid phosphatase inhibitor, is a sodium salt used in buffers for molecular biology and cell culture applications. Tartaric acid disodium dihydrate increases the rate of colchicine binding to tubulin1. |
| M43528 | YF704 | YF704 is a selective allosteric inhibitor of SHP2 (IC50=0.25 μM). |
| M43527 | CNBCA | CNBCA is a potent, selective, competitive SHP2 enzyme inhibitor, with the IC50 of 0.87 μM. |
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