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cis-Ferulic acid 4-O-β-D-glucopyranoside

Cat. No. M42547
cis-Ferulic acid 4-O-β-D-glucopyranoside Structure
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Biological Activity

cis-Ferulic acid 4-O-β-D-glucopyranoside is a phenolic glycosid, which can be isolated from Nitraria sibirica..

Chemical Information
Molecular Weight 356.32
Formula C16H20O9
CAS Number 94942-20-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Chen Huo et al. Plants (Basel). Global Natural Products Social (GNPS)-Based Molecular-Networking-Guided Isolation of Phenolic Compounds from Ginkgo biloba Fruits and the Identification of Estrogenic Phenolic Glycosides

[2] Sullim Lee et al. Antioxidants (Basel). Laricitrin 3-Rutinoside from Ginkgo biloba Fruits Prevents Damage in TNF-α-Stimulated Normal Human Dermal Fibroblasts

[3] Chimengul Turghun et al. Nat Prod Res. Phenolic glycosides from Nitraria sibirica leaves and their in vitro biological activities

[4] Sileshi G Wubshet et al. J Nat Prod. Magnetic Ligand Fishing as a Targeting Tool for HPLC-HRMS-SPE-NMR: α-Glucosidase Inhibitory Ligands and Alkylresorcinol Glycosides from Eugenia catharinae

[5] Wei-Hua Huang et al. Zhongguo Zhong Yao Za Zhi. [Phenolic constituents from Oplopanax horridus]

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Keywords: cis-Ferulic acid 4-O-β-D-glucopyranoside supplier, Phosphatase, inhibitors, activators


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