Free shipping on all orders over $ 500

 About 30 results found for searched term "Phosphatase" (0.013 seconds)

Cat.No.  Name Information
M1831 Cyclosporine A Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. cyclosporin A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation.
M2849 Microcystin-LR Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
M2865 Sodium Monofluorophosphate Monofluorophosphate is a competitive inhibitor of pyruvate kinase and alkaline phosphatase with Ki of 3.4 mM and 69 μM, respectively, which also irreversibly inhibits phosphorylase phosphatase with Ki of 0.5 mM.
M2922 Pentamidine Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.
M2993 Sal003 Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor.
M3837 β-Glycerophosphate disodium salt hydrate β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers.
M3943 Sanguinarine Sanguinarine, a plant alkaloid with anti-proliferative effects against cancers, is a potent and specific protein phosphatase (PP) 2C inhibitor.
M4562 Cantharidin Cantharidin is a natural toxin inhibitor of protein phosphatases 1 and 2A (Ki values are 1.1 and 0.19 μM respectively). Displays > 500-fold selectivity over PP2B.
M4596 Silydianin Silydianin, the active ingredient of silythistle, has anti-collagenase and anti-elastic enzyme activities. Silydianin is a natural protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 17.38 μM. Silydianin inhibited the production and release of oxidation products in vitro.
M21540 L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) is a long-term vitamin C derivative that can stimulate the expression and formation of collagen. L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) can be used as a medium to supplement osteogenic differentiation of human adipose stem cells (hASCs). Increased alkaline phosphatase (ALP) activity and runx2A expression in hASC during osteoblast differentiation.
M5102 PTP1B-IN-2 PTP1B-IN-2 is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM.
M5161 Sodium orthovanadate Sodium orthovanadate is an alkaline phosphatase and (Na,K)-ATPase inhibitor with IC50 of 10 μM.
M5195 Okadaic acid Okadaic acid is a potent inhibitor of protein phosphatase 1/2A with IC50 values of 19 nM and 0.2 nM for protein phosphatase 1 and protein phosphatase 2A, respectively.
M8990 LB-100 LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor, with IC50 of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.
M5348 (-)-Tetramisole (-)-Tetramisole is an inhibitor of alkaline phosphatase, used as an anthelmintic.
M5632 Etidronate Etidronate is a class of non-aminobisphosphate that inhibits human protein tyrosine phosphatase activity and is used in the study of Paget's disease and in the prevention of ectopic ossification.
M5767 Menadione(Vitamin K3) Menadione(Vitamin K3), a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.
M5869 Pentamidine isethionate Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.
M5986 Suramin sodium salt Suramin Sodium Salt (Suramin hexasodium salt) is a reversible inhibitor of competitive protein tyrosine phosphatases (PTPases).
M6293 Tacrolimus monohydrate Tacrolimus monohydrate binds to FK506 binding protein (FKBP). This complex inhibits calcineurin phosphatase (PP2B). Tacrolimus monohydrate is a mTOR-independent autophagy inducer.
M6300 (-)-p-Bromotetramisole Oxalate (-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.
M6383 A12B4C3 A12B4C3 is a potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor.
M6542 BVT 948 BVT 948 is a non-competitive protein tyrosine phosphatase inhibitor; enhances insulin signaling.
M6727 PFK-158 PFK-158, also known as ACT-PFK-158, is a potent and selective inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) with potential antineoplastic activity.
M6770 GSK 2830371 GSK 2830371 is a potent and selective allosteric inhibitor of Wip1 phosphatase.
M6881 L-690,330 L-690,330 is a inositol monophosphatase inhibitor.
M7057 NSC 663284 NSC 663284 is a potent, selective Cdc25 phosphatase inhibitor.
M7059 NSC 87877 Nsc-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatase with IC50 values of 0.318 μM and 0.355 μM, respectively. Nsc-87877 also inhibits bispecific phosphatase 26 (DUSP26).
M7060 NSC 95397 NSC 95397 is a selective Cdc25 dual specificity phosphatase inhibitor.
M7246 Sanguinarine chloride Sanguinarine chloride is a inhibitor of protein phosphatase 2C (PP2C).

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.