All AbMole products are for research use only, cannot be used for human consumption.
C2 Ceramide (N-Acetyl-D-sphingosine) is a cell-permeable and biologically active ceramide, it induces differentiation and apoptosis in cells and has been shown to activate protein phosphatases. C2 Ceramide (N-Acetyl-D-sphingosine) produces concentration-dependent impairment of vasorelaxation in response to the endothelium-dependent agonist acetylcholine in nontransgenic mice.
| Molecular Weight | 341.53 |
| Formula | C20H39NO3 |
| CAS Number | 3102-57-6 |
| Solubility (25°C) | Soluble in DMSO Soluble in ethanol |
| Storage | -20°C, dry, sealed |
[1] P A Hill, et al. J Endocrinol. Ceramide-induced cell death/survival in murine osteoblasts
[2] R T Dobrowsky, et al. J Biol Chem. Ceramide activates heterotrimeric protein phosphatase 2A
[3] R T Dobrowsky, et al. J Biol Chem. Ceramide stimulates a cytosolic protein phosphatase
| Related Phosphatase Products |
|---|
| RMC-3943
RMC-3943 is an allosteric SHP2 inhibitor (inhibition of full-length SHP2 in biochemical assay, IC50 = 2.19 nM). |
| LYP-IN-1
LYP-IN-1 is a potent, selective and specific LYP inhibitor with a Ki and an IC50 of 110 nM and 0.259 μM, respectively. |
| PF-07284892
PF-07284892 (ARRY-558) is a potent and orally active SHP2 inhibitor with an IC50 value of 21 nM. |
| MY10
MY10 is a potent and orally active receptor protein tyrosine phosphatase (RPTPβ/ζ) inhibitor. |
| CPDA
CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
