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BTdCPU is an potent activator of HRI, it promotes eIF2α phosphorylation and induced apoptosis in resistant cell. Combination therapy with rapamycin and BTdCPU, demonstrated additive effects on apoptosis in dex-resistant cells.
| Molecular Weight | 339.20 |
| Formula | C13H8Cl2N4OS |
| CAS Number | 1257423-87-2 |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Phosphatase Products |
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RMC-3943 is an allosteric SHP2 inhibitor (inhibition of full-length SHP2 in biochemical assay, IC50 = 2.19 nM). |
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| PF-07284892
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| MY10
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| CPDA
CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor. |
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