GluR Glutamate receptor

Cat.No.	Name	Information
M2767	Ifenprodil Tartrate	Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM.
M9566	Glycine	Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate.
M2884	NMDA	NMDA（N-Methyl-D-aspartic acid）is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.
M3003	CB-839	Telaglenastat (CB-839) is a potent, selective, and orally bioavailable glutaminase inhibitor with IC50 of 24 nM for recombinant human GAC.
M4956	L-701324	L-701324 is a long-acting oral anticonvulsant compound with high affinity and selectivity for glycine sites on NMDA receptors.
M4950	Topiramate	Topiramate is an anticonvulsant that antagonizes GluR5 receptors and acts as a positive allosteric modulator of GABA receptor-mediated currents.
M4833	Eliprodil	Eliprodil is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM).
M3904	Pulchinenoside A	Pulchinenoside can inhibit abnormal proliferation of synovial membrane by modulating Wnt pathway of RA rats.Pulchinenoside may inhibit the FLS proliferation in AA rats by increase in FLS apoptosis.
M3806	GLYX-13	GLYX-13 is a selective weak partial agonist of the glycine site of the NMDA receptor.
M3445	ADX-47273	ADX47273 is a potent and specific mGlu5 positive allosteric modulator(PAM) with EC50 of 0.17 μM, showing no activity at other mGlu subtypes.
M3279	GYKI-52466	GYKI-52466 is a non-competitive AMPA/kainate antagonists with IC50 of 7.5 μM and 11 μM, respectively.
M3189	TCN-201	TCN 201 is a NMDA receptor antagonist for NR1/NR2A and NR1/NR2B with pIC50 of 6.8 and 4.3, respectively.
M3126	VU 0357121	VU0357121 is a novel positive allosteric modulator (PAM) of mGlu5 with EC50 of 33 nM, is inactive or very weakly antagonizing at other mGlu receptor subtypes.
M3125	VU 0364770	VU 0364770 is a positive allosteric modulator(PAM) of mGlu4 with EC50 of 1.1 μM, exhibits insignificant activity at 68 other receptors, including other mGlu subtypes.
M3124	VU 0364439	VU 0364439 is a mGlu4 positive allosteric modulator (PAM), with EC50 of 19.8 nM.
M2962	Procyclidine hydrochloride	Procyclidine hydrochloride blocks the effects of certain chemicals in the brain, and thus is used to treat Parkinson's disease or extrapyramidal side-effects caused by other medicines.
M2867	MPEP hydrochloride	MPEP hydrochloride is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.
M2766	IEM 1754 dihydrobromide	IEM 1754 dihydrobroMide is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
M2584	MDL-29951	MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo with IC50 value of 0.14 mM ([3H]glycine binding).
M2581	Ampalex	Ampalex is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator which can be used for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).
M2576	VU 0361737	VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively.
M2542	CTEP	CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors.
M2253	Felbamate	Felbamate(Felbatol) is an anticonvulsant compound used in epilepsy research.
M1926	LY404039	LY404039 is a potent, selective and orally active agonist of recombinant human mGlu2, mGlu3 receptors with Ki of 149 nM, 92 nM respectively.

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GluR Glutamate receptor

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