All AbMole products are for research use only, cannot be used for human consumption.
CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors.
| Molecular Weight | 391.77 |
| Formula | C19H13ClF3N3O |
| CAS Number | 871362-31-1 |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Vivek Subbiah, et al. Advances in Targeting RET-Dependent Cancers
[4] Haifeng Zhang, et al. CTEP Versus LESS Totally Extraperitoneal Hernioplasty
| Related GluR Products |
|---|
| VU0650786
VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. |
| NS-102
NS-102 is a selective kainate (GluK2) receptor antagonist. |
| VU0424465
VU0424465 is a potent and partial PAM (positive allosteric modulator)-agonist for mGlu5 mediated iCa2+ mobilization. |
| ATPA
ATPA is a selective glutamate receptor GluR5 activator with EC50s of 0.66, 9.5, 1.4, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S741M), GluR5(S721T), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V), respectively. |
| (R)-CPP
(R)-CPP is a highly potent NMDA receptor antagonist. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
