GluR Glutamate receptor

Inhibitors

Cat.No.	Name	Information
M2767	Ifenprodil Tartrate	Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM.
M9566	Glycine	Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate.
M5740	L-Glutamine	L-Glutamine (Gln) is one of the 20 amino acids encoded by the standard genetic code and also a major respiratory fuel and substrate for nucleic acid synthesis in mammalian intestinal cells.
M14233	Tat-NR2B9c TFA	Tat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC₅₀ values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively.
M14232	Rapastinel Trifluoroacetate	Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties. Rapastinel Trifluoroacetate has the potential for major depressive disorder treatment.
M14231	PEAQX tetrasodium hydrate	PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B, respectively.
M14230	Naspm trihydrochloride	Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
M14229	Naspm	Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
M14228	MRZ 2-514	MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with Ki of 33 μM.
M14227	LY450108	LY450108 is a potent AMPA receptor potentiator. LY450108 has the potential for depression and Parkinson's disease research.
M14226	Bupivacaine	Bupivacaine is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC₅₀ of 69.5 μM.
M14018	Basimglurant	Basimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a K_d of 1.1 nM.
M14017	Mavoglurant	Mavoglurant (AFQ056) is a potent, selective, non-competitive and orally active mGluR5 antagonist, with an IC₅₀ of 30 nM.
M14016	DHPG	DHPG ((RS)-3,5-DHPG) is an amino acid, which acts as a selective and potent agonist of group I mGluR (mGluR 1 and mGluR 5), shows no effect on Group II or Group III mGluRs.
M14015	(RS)-MCPG	(RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons.
M10378	Cycloleucine	Cycloleucine is antagonist of NMDA receptor associated glycine receptor, with a Ki of 600 μM. Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation.
M9869	L-Methionine sulfoximine	L-Methionine sulfoximine is a potent inhibitor of glutamine sythetase (GS) activity, used as a selection agent for plasmid integration in Chinese hamster ovary (CHO) and other mammalian cell lines.
M9646	Decoglurant	Decoglurant (also known as RO4995819) is a negative allosteric modulator of the mGlu2 and mGlu3 receptors.
M9566	Glycine	Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate.
M7707	CX546	CX546 is a selective positive AMPA glutamate receptor modulator.
M7581	(+)-MK 801 Maleate	(+)-MK 801 (Maleate) is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
M7565	JNJ-42153605	JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor with an EC50 of 17 nM.
M7111	PEPA	PEPA is a allosteric potentiator of AMPA receptor desensitization.

Signaling Pathways

Product Type

GluR Glutamate receptor

Get to Know Us

Customer Support

Resources

Contact Us