Cat.No. | Name | Information |
---|---|---|
M2767 | Ifenprodil Tartrate | Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM. |
M9566 | Glycine | Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate. |
M2884 | NMDA | NMDA(N-Methyl-D-aspartic acid)is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. |
M3003 | CB-839 | Telaglenastat (CB-839) is a potent, selective, and orally bioavailable glutaminase inhibitor with IC50 of 24 nM for recombinant human GAC. |
M14233 | Tat-NR2B9c TFA | Tat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. |
M14231 | PEAQX tetrasodium hydrate | PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B, respectively. |
M14230 | Naspm trihydrochloride | Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. |
M14229 | Naspm | Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. |
M14228 | MRZ 2-514 | MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with Ki of 33 μM. |
M10378 | Cycloleucine | Cycloleucine is antagonist of NMDA receptor associated glycine receptor, with a Ki of 600 μM. Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation. |
M9894 | DL-2-Amino-5-phosphonopentanoic acid | DL-2-Amino-5-phosphonopentanoic acid has been used in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses. |
M9869 | L-Methionine sulfoximine | L-Methionine sulfoximine is a potent inhibitor of glutamine sythetase (GS) activity, used as a selection agent for plasmid integration in Chinese hamster ovary (CHO) and other mammalian cell lines. |
M9646 | Decoglurant | Decoglurant (also known as RO4995819) is a negative allosteric modulator of the mGlu2 and mGlu3 receptors. |
M8892 | Coluracetam | Coluracetam (MKC-231) is a new choline uptake enhancer. |
M8889 | 6-Methoxy-2-naphthoic acid | 6-Methoxy-2-naphthoic acid is an NMDA receptor modulator. |
M8367 | Ro 25-6981 maleate salt | Ro 25-6981 maleate salt is a potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit with IC50 values of .009 μM for NR2B vs. 52 μM for NR2A subunits. Ro 25-6981 has been shown to have neuroprotectant effects and to reduce inflammatory and neuropathic pain in rodent models. |
M8242 | ZL006 | ZL006 inhibits the ischemia-induced interaction of nNOS with postsynaptic density protein-95 (PSD-95), preventing glutamate-induced excitotoxicity and cerebral ischemic damage. |
M7760 | DM 235 | DM 235 (Sunifiram) is an effective nootropics compound. |
M7707 | CX546 | CX546 is a selective positive AMPA glutamate receptor modulator. |
M7565 | JNJ-42153605 | JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor with an EC50 of 17 nM. |
M7553 | Farampator | Farampator (CX-691;Org24448) is an AMPA receptor positive modulator. |
M7294 | SIB 1893 | SIB 1893 is a mGlu 5 antagonist and positive allosteric modulator at mGlu 4. |
M7175 | QNZ 46 | QNZ 46 is a nR2C/NR2D-selective NMDA receptor non-competitive antagonist. |
M7130 | PHCCC | PHCCC is a potent group I mGlu antagonist. |
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