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QNZ 46 is a nR2C/NR2D-selective NMDA receptor non-competitive antagonist (IC50 values are 3, 6, 229, and >300, >300 μM for NR2D, NR2C, NR2A, NR2B, and GluR1, respectively). Requires binding of glutamate to the GluN2 subunit.
| Molecular Weight | 443.41 |
| Formula | C24H17N3O6 |
| CAS Number | 1237744-13-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 4.43 mg/mL (with gentle warming) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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| NS-102
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| VU0424465
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| ATPA
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| (R)-CPP
(R)-CPP is a highly potent NMDA receptor antagonist. |
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