Cat.No. | Name | Information |
---|---|---|
M2767 | Ifenprodil Tartrate | Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM. |
M9566 | Glycine | Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate. |
M2884 | NMDA | NMDA(N-Methyl-D-aspartic acid)is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. |
M3003 | CB-839 | Telaglenastat (CB-839) is a potent, selective, and orally bioavailable glutaminase inhibitor with IC50 of 24 nM for recombinant human GAC. |
M56499 | Neboglamine hydrochloride | Neboglamine (CR-2249, XY-2401) hydrochloride is an orally active NMDA receptor glycine site positive modulator that can be used in schizophrenia research. |
M56498 | SDZ 220-581 Ammonium salt | SDZ 220-581 Ammonium salt is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7. |
M56497 | GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride is an orally active, highly selective and noncompetitive AMPA/kainate receptor antagonist with the IC50 values of 7.5 and 11μM, respectively. |
M56496 | GYKI-47261 dihydrochloride | GYKI-47261 dihydrochloride is a competitive, orally active, and selective AMPA receptor antagonist with an IC50 of 2.5 μM. |
M56495 | (R,S)-3,4-Dicarboxyphenylglycine | (R,S)-3,4-Dicarboxyphenylglycine ((RS)-3,4-DCPG) is an AMPA receptor antagonist. |
M56494 | Pregnanolone sulfate (pyridinium) | Pregnanolone sulfate pyridinium is an endogenous neurosteroid that inhibits NMDA receptors and is neuroprotective. |
M56493 | 5,7-Dichlorokynurenic acid sodium | 5,7-Dichlorokynurenic acid (sodium) is the sodium form of 5,7-Dichlorokynurenic acid. |
M56278 | (RS)-APICA | (RS)-APICA is a selective group II metabotropic glutamate receptor (mGluR II) antagonist. |
M56277 | (RS)-PPG | (RS)-PPG is a potent and selective agonist for group III mGluRs. |
M56276 | (2R,4R)-APDC | (2R,4R)-APDC is a group II metabotropic glutamate receptor (mGluR) agonist. |
M56275 | (S)-3,5-DHPG | (S)-3,5-DHPG is a weak, but selective group I metabotropic glutamate receptors (mGluRs) agonist with Ki values of 0.9 µM and 3.9 µM for mGluR1a and mGluR5a, respectively. |
M56274 | LSN2463359 | LSN2463359 is positive allosteric modulator of metabotropic glutamate 5 (mGlu5). |
M56273 | (1S,3R)-ACPD | (1S,3R)-ACPD is a mGluR agonist that can depolarize pyramidal cells. |
M56272 | (±)-LY395756 | (±)-LY395756 is an agonist of mGlu2 receptor and an antagonist of mGlu3 receptor. |
M56271 | Desmethyl-YM-298198 | Desmethyl-YM-298198 is a high-affinity, selective, and noncompetitive mGluR1 antagonist (IC50: 16 nM). |
M56270 | MFZ 10-7 hydrochloride | MFZ 10-7 hydrochloride is a highly potent and selective mGluR5 NAM (negative allosteric modulator), with a Ki of 0.67 nM for rat mGluR5. |
M56269 | (S)-3-Hydroxyphenylglycine | (S)-3-Hydroxyphenylglycine ((S)-3HPG) is a potent mGluR1 agonist without effect at mGlu2 or mGlu4. |
M56268 | Raseglurant hydrochloride | Raseglurant hydrochloride is a negative allosteric modulator of mGluR5. |
M56267 | Desmethyl-YM-298198 hydrochloride | Desmethyl-YM-298198 hydrochloride is a high-affinity, selective, and noncompetitive mGluR1 antagonist (IC50: 16 nM). |
M56266 | L-Cysteinesulfinic acid monohydrate | L-Cysteinesulfinic acid monohydrate is a potent agonist at several rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively. |
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