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UPGL00004

Cat. No. M20645

All AbMole products are for research use only, cannot be used for human consumption.

UPGL00004 Structure
Size Price Availability Quantity
10mg USD 160  USD160 In stock
25mg USD 310  USD310 In stock
50mg USD 530  USD530 In stock
100mg USD 900  USD900 In stock
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Quality Control & Documentation
Biological Activity

UPGL00004 is a potent glutaminase C (GAC) inhibitor with an IC50 of 29 nM, showing high selectivity for GAC over GLS2.

Chemical Information
Molecular Weight 534.66
Formula C25H26N8O2S2
CAS Number 1890169-95-5
Solubility (25°C) DMSO 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Luqman Shah, et al. RSC Adv. Recombinant l-glutaminase obtained from Geobacillus thermodenitrificans DSM-465: characterization and in silico elucidation of conserved structural domains

[2] Qingqiu Huang, et al. J Biol Chem. Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism

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Abmole Inhibitor Catalog




Keywords: UPGL00004 supplier, GluR, inhibitors, activators

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