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Felbamate(Felbatol) is an anticonvulsant compound used in epilepsy research.
 |
Source | Epilepsy Behav (2017). Figure 4. Felbamate |
| Method | Drug administration | |
| Cell Lines | Sprague–Dawley rats | |
| Concentrations | 3000 mg/rat | |
| Incubation Time | 5 d | |
| Results | In the absence of prior appetitive experience, a quite different pattern emerges, with the FBM-treated rats showing an acquisition deficit that persists throughout much of the training |
 |
Source | Epilepsy Behav (2017). Figure 3. Felbamate |
| Method | Drug administration | |
| Cell Lines | Sprague–Dawley rats | |
| Concentrations | 3000 mg/rat | |
| Incubation Time | 5 d | |
| Results | FBM-treated animals showed enhanced acquisition in the aversive context with prior appetitive training relative to controls |
| Cell Experiment | |
|---|---|
| Cell lines | Follicle cells |
| Preparation method | Drug solutions were diluted into recording MBS from frozen stocks (NMDA, glycine) or dissolved from powder directly into MBS (felbamate, haloperidol) on the day of the experiment. Felbamate was dissolved in MBS to the highest concentration used (up to 3 mM) by heating to 50°C followed by vigorous stirring. The process was repeated once or twice, as necessary, until the felbamate dissolved. |
| Concentrations | 1~3 mM |
| Incubation time | 24 h |
| Animal Experiment | |
|---|---|
| Animal models | |
| Formulation | |
| Dosages | |
| Administration | |
| Molecular Weight | 238.24 |
| Formula | C11H14N2O4 |
| CAS Number | 25451-15-4 |
| Solubility (25°C) | DMSO 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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