| Cat.No. | Name | Information |
|---|---|---|
| M2347 | (+)-Bicuculline | (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels. |
| M5442 | Baclofen | Baclofen is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research. |
| M5653 | Flumazenil | Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses. |
| M52787 | CGP7930 | CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. |
| M44709 | 3,4,5-Trimethoxy-trans-cinnamic acid | (E)-3,4,5-Trimethoxycinnamic acid (TMCA) is a cinnamic acid substituted by multi-methoxy groups. |
| M42191 | NCS-382 sodium | NCS-382 (sodium) is a potent GABA receptor antagonist. |
| M42190 | MRK-898 | MRK-898 is an orally active GABA(A) receptor modulator. |
| M42189 | ZAPA sulfate | ZAPA sulfate is an agonist at low affinity GABAA-receptors. |
| M42188 | Xilmenolone | Xilmenolone is a GABAA receptor positive allosteric modulator. |
| M42187 | NNC 05-2090 | NNC 05-2090 is a potent inhibitor of mGAT2, with a Ki of 1.4 μM. |
| M42186 | Arecaidine hydrobromide | Arecaidine hydrobromide, a pyridine alkaloid, is a potent GABA uptake inhibitor. |
| M42185 | Muscimol hydrochloride | Muscimol hydrochloride is a potent GABAA receptor agonist (EC50=0.2 μM), partial GABAC receptor agonist and inactive GABAB receptor agonist. |
| M42183 | Panadiplon | Panadiplon (FG 10571; PNU 78875), a benzodiazepine receptor, is a 5GABAA partial agonist. |
| M42182 | α5IA | α5IA (L-822179) is a selective α5 GABAA receptor inverse agonist with neuroprotective potential. |
| M42181 | 3-Methylglutaconic acid | 3-Methylglutaconic acid is the major metabolites accumulating in 3-Methylglutaconic aciduria (MGTA). |
| M42180 | Guvacine hydrobromide | Guvacine hydrobromide, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. |
| M42179 | CGS 20625 | CGS 20625 is a potent, selective and orally active partial agonist for the central benzodiazepine receptor. |
| M42178 | 1-Phenyl-2-pyrrolidinone | 1-Phenyl-2-pyrrolidinone (1-Phenylpyrrolidin-2-one) is a phenyl analogue of GABA with sedative effect, decreasing the exploratory behavior of rats at 50-100 mg/kg (i.v.). |
| M42177 | SCS | SCS (Salicylidene salicylhydrazide) is a potent, allosteric and selective inhibitor of β1-containing GABAA receptors with an IC50 of 32 nM against α2β1γ1θ by VIPR measurement. |
| M39028 | Picrotin | Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission. |
| M39027 | Isohyenanchin | Isohyenanchin (Hydroxycoriatin) is an RDLac homo-oligomers antagonist. Isohyenanchin also is a weak antagonist of ionotropic GABA receptors. |
| M39026 | Chrodrimanin B | Chrodrimanin B is a potent, non-open-channel-blocking antagonist on B. mori GABAR RDL with an IC50 of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50 of 1.66 nM. |
| M39025 | Isonipecotic acid | Isonipecotic acid is a GABAA receptor partial agonist. |
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