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Chrodrimanin B

Cat. No. M39026

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Chrodrimanin B Structure
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Biological Activity

Chrodrimanin B is a potent, non-open-channel-blocking antagonist on B. mori GABAR RDL with an IC50 of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50 of 1.66 nM.

Chemical Information
Molecular Weight 484.54
Formula C27H32O8
CAS Number 132196-54-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Makoto Ihara et al. Pestic Biochem Physiol. Competitive chrodrimanin B interactions with rat brain GABAA receptors revealed by radioligand binding assays

[2] Tongxuan Bai et al. Org Lett. Elucidation and Heterologous Reconstitution of Chrodrimanin B Biosynthesis

[3] Jia Guo et al. Appl Microbiol Biotechnol. Tafuketide, a phylogeny-guided discovery of a new polyketide from Talaromyces funiculosus Salicorn 58

[4] Yan Xu et al. PLoS One. Meroterpenoid Chrodrimanins Are Selective and Potent Blockers of Insect GABA-Gated Chloride Channels

[5] Hideo Hayashi et al. Biosci Biotechnol Biochem. A new meroterpenoid, chrodrimanin C, from YO-2 of Talaromyces sp

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Keywords: Chrodrimanin B supplier, GABA Receptor, inhibitors, activators

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