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Baclofen is a gamma-amino-butyric acid (GABA) derivative. Baclofen is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research.
Patent. CN115154451B 2023 Oct 13.
Patent. CN115154451B
Baclofen purchased from AbMole
| Molecular Weight | 213.66 |
| Formula | C10H12ClNO2 |
| CAS Number | 1134-47-0 |
| Solubility (25°C) | DMSO 4 mg/mL (ultrasonic and warming and adjust pH to 4 with HCl) 0.1 M HCl: 9 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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