Certificate of Analysis
| Product Name: | Baclofen |
| Catalog Number: | M5442 |
| CAS Number: | 1134-47-0 |
Physical and Chemical Properties
| Formula: | C10H12ClNO2 |
| Molecular Weight: | 213.66 |
| Solubility: | DMSO 4 mg/mL (ultrasonic and warming and adjust pH to 4 with HCl); 0.1 M HCl: 9 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.28% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Baclofen is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |