| Cat.No. | Name | Information |
|---|---|---|
| M2347 | (+)-Bicuculline | (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels. |
| M4231 | Ginkgolide-A | Ginkgolide A (BN-52020) is A GABA antagonist extracted from ginkgo biloba leaves. |
| M4073 | Ginsenoside-Rc | Ginsenoside Rc is one of the major ginsenosides. Ginsenoside Rc enhances GABA receptor A (GABAA) -mediated ion channel (IGABA) currents. Ginsenoside Rc also inhibited TNF-α and IL-1β expression. |
| M4019 | Songorine | Songorine is a diterpenoid alkaloid isolated from the genus Aconite. Songorine is a GABAA receptor antagonist in rat brain and has anticancer, anti-arrhythmia and anti-inflammatory activities. Songorine has potential to be used in epithelial ovarian cancer (EOC) studies. |
| M4013 | Glabridin | Glabridin, one of the active phytochemicals in licorice extract, binds to and activates the ligand binding domain of PPARγ, as well as the full length receptor. It is also a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory. |
| M3981 | Bilobalide | Bilobalide, a natural product extracted from Ginkgo biloba leaf, is known to exhibit a number of pharmacological activities. |
| M3968 | Dihydromyricetin | Dihydromyricetin is a natural antioxidant flavonoid from Ampelopsis grossedentata. |
| M3938 | Baicalin | Baicalin is an allosteric carnitine palmityl transferase 1 (CPT1) activator. Baicalin reduces the expression of NF-κB. |
| M3600 | Gabapentin | Gabapentin is a pharmaceutical agent, specifically a GABA analogue. |
| M3599 | Pregabalin | Pregabalin (Lyrica) is a 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities. |
| M3376 | Chlormezanone | Chlormezanone，a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm. |
| M3344 | Nefiracetam | Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions. |
| M2949 | Piracetam | Piracetam is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders. |
| M2555 | AWD 131-138 | AWD 131-138 is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models. |
| M2439 | Bemegride | Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning. |
| M2005 | (R)-Baclofen | (R)-baclofen, a gamma-aminobutyric acid derivative and agonist at GABA-B receptors, inhibits nerve conduction in the central nervous system and can be used in studies related to spasticity. |
| M1954 | Alpidem | Alpidem is a potent antagonist of peripheral benzodiazepine receptor (PBR). |
| M1891 | SKF 89976A hydrochloride | SKF 89976A hydrochloride is a potent GABA uptake inhibitor, selective for GAT-1. |
| M56489 | β-CCB | β-CCB is a ligand for benzodiazepine receptor, which inhibits the binding of [3H]flunitrazepam and ethyl (3-[3H]carboline-3-carboxylate to benzodiazepine receptors, with Ki of 3-4 nM. |
| M56488 | TPMPA | TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABAC receptor (KB = 2.1 μM), but not to interact with GABAA (KB = 320 μM) or GABAB receptors (EC50 = 500 μM). |
| M56487 | CI-966 | CI-966 is a potent, selective, orally active and brain-penetrant inhibitor of the GABA transporter GAT-1, with IC50s of 0.26 μM and 1.2 μM for hGAT-1, rGAT-1, respectively. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
