| Cat.No. | Name | Information |
|---|---|---|
| M2347 | (+)-Bicuculline | (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels. |
| M56486 | NCS-382 | NCS-382 is a potent GABA receptor antagonist and also a GHBR receptor antagonist. |
| M56485 | CGS 8216 | CGS 8216, a benzodiazepine receptor antagonist, inhibits 3H-flunitrazepam (3H-FLU) binding to rat synaptosomal membranes in vitro at subnanomolar concentrations. |
| M56484 | CGP13501 | CGP13501 is a positive allosteric modulator of GABAB receptor. |
| M56483 | TPA-023B | TPA-023B is a high-affinity and orally active GABAA receptor α2/α3 subtype (Kis of 0.73 nM/2 nM) partial agonist and a α1 subtype (Ki of 1.8 nM) antagonist. |
| M56482 | CGP46381 | CGP 46381 is an orally active GABAB receptor antagonist with IC50 of 4.9 μM. |
| M56481 | CGP35348 | CGP 35348 is a selective, brain penetrant, centrally active GABAB receptor antagonist with an EC50 of 34 μM. CGP 35348 shows affinity for the GABAB receptor only. |
| M56480 | SCH 50911 | SCH 50911, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. |
| M56479 | Phaclofen | Phaclofen is a selective GABAB receptor antagonist. |
| M56478 | Lorediplon | Lorediplon is a novel non-benzodiazepine drug acting as a GABAA receptor modulator, differentially active at the alpha1-subunit, associated with promoting sleep. |
| M56477 | Lesogaberan | Lesogaberan (AZD-3355) is a potent and selective GABAB receptor agonist with an EC50 of 8.6 nM for human recombinant GABAB receptors. |
| M56476 | 3-Methyl-GABA | 3-Methyl-GABA is a potent GABA aminotransferase activator. |
| M56475 | CI-966 hydrochloride | CI-966 hydrochloride is a potent, selective, orally active and brain-penetrant inhibitor of the GABA transporter GAT-1, with IC50s of 0.26 μM and 1.2 μM for hGAT-1, rGAT-1, respectively. |
| M56474 | CGP36216 hydrochloride | CGP36216 hydrochloride is a selective antagonist at GABA presynaptic receptor. |
| M56473 | SCH 50911 hydrochloride | SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. |
| M56472 | Lesogaberan napadisylate | Lesogaberan (AZD-3355) napadisylate is a potent and selective GABAB receptor agonist with an EC50 of 8.6 nM for human recombinant GABAB receptors. |
| M56471 | Lesogaberan hydrochloride | Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABAB receptor agonist with an EC50 of 8.6 nM for human recombinant GABAB receptor. |
| M56470 | Loreclezole hydrochloride | Loreclezole hydrochloride, an antiepileptic compound, is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit containing receptors. |
| M56469 | 6,2'-Dihydroxyflavone | 6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor. |
| M56468 | Tetrahydrodeoxycorticosterone | Tetrahydrodeoxycorticosterone, an neurosteroid, is a potent positive allosteric modulator (PAM) of GABAA receptor. |
| M54859 | Alogabat | Alogabat (RG-7816) is a GABAA α5 receptor positive allosteric modulators (PAMs). |
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