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Baicalin facilitated the transfer of electrons from Fe (2+) to dissolved oxygen. Baicalin has the capacity to protect IEC-6 cells and the intercellular tight junctions from LPS-induced injury. The mechanisms may be associated with inhibiting the production of inflammatory cytokines, and up-regulating the mRNA and protein expression of ZO-1. Baicalin had no effects on the pharmacokinetics of caffeine and its metabolites in vivo, following single oral administration in rats. Anti-inflammatory properties of baicalin may be resulted from the inhibition of IL-6, IL-8, and TNF-α expression via preventing signaling NF-κB pathway in HBE16 airway epithelial cells.
| Molecular Weight | 446.36 |
| Formula | C21H18O11 |
| CAS Number | 21967-41-9 |
| Solubility (25°C) | DMSO ≥ 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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