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Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission.
| Molecular Weight | 310.3 |
| Formula | C15H18O7 |
| CAS Number | 21416-53-5 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL (ultrasonic) |
| Storage | Powder -20°C |
[1] Ping Li et al. Neuroreport. Gating effects on picrotin block of glycine receptors
[4] S N SLATER et al. Nature. Relationship between picrotin and picrotoxinin
| Related GABA Receptor Products |
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Pregabalin-d4 |
| Alogabat
Alogabat (RG-7816) is a GABAA α5 receptor positive allosteric modulators (PAMs). |
| CGP7930
CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. |
| 5-Aminovaleric acid
5-Aminovaleric acid is a GABA receptor antagonist. |
| L-2,4-Diaminobutyric acid dihydrochloride
L-2,4-Diaminobutyric acid dihydrochloride inhibits GABA transaminase activity, resulting in elevated GABA levels, and exhibits ex vivo antitumor activity against mouse fibrosarcoma cells. In addition, L-2,4-Diaminobutyric acid dihydrochloride can be used as an internal standard for amino acid analysis. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
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