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  Catalog
Abmole Inhibitor Catalog 2017

Ferroptosis Ferroptosis

Inhibitors

Cat.No.  Name Information
M10244 Imidazole ketone erastin Imidazole ketone erastin (IKE) is an inducer of ferroptosis, and it is also a potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter, system Xc-.
M9404 UAMC-3203 hydrochloride UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor, with an IC50 of 12 nM.
M9060 RSL3 RSL3 is an inhibitor of the glutathione (GSH) peroxidase 4, which can inhibit the cysteine/glutamate amino acid transporter system.
M8531 Liproxstatin-1 Liproxstatin-1 is a potent inhibitor of ferroptosis, a non-apoptotic form of cell death characterized by iron-dependent accumulation of lethal lipid reactive oxygen species (ROS).
M7504 CIL56 (CA3) CIL56 (CA3) is a potent and selective ferroptosis inducer, it has potent inhibitory effects on YAP1/Tead transcriptional activity and primarily targets YAP1 high and therapy-resistant esophageal adenocarcinoma cells endowed with CSC properties.
M6731 FIN56 FIN56 is a ferroptosis activator.
M5558 Deferoxamine mesylate Deferoxamine mesylate as a chelating agent used to remove excess iron from the body.
M3400 Idebenone Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant.
M2698 Ferrostatin-1 Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.
M2679 Erastin Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. *The compound is unstable in solutions, freshly prepared is recommended


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