| Cat.No. | Name | Information |
|---|---|---|
| M3895 | Liquiritin | Liquiritin is a major constituent of Glycyrrhiza Radix that has a neuroprotective effect against glutamate toxicity in DPC12 cells. |
| M3894 | Rutin | Rutin is a flavonol glycoside found in many plants including buckwheat, tobacco, forsythia, hydrangea, viola, etc., which possesses healthy effects for human. |
| M3883 | 20(S)-Protopanaxatriol | 20(S)-Protopanaxatriol (PPT), one of the aglycones of ginsenosides, has been shown to exert cardioprotective effects against myocardial ischemic injury. |
| M3826 | Papain | Papain is a cysteine protease of the peptidase C1 family. |
| M3809 | Isofraxidin | Isofraxidin is an anti-bacterial, anti-oxidant, and anti-inflammatory agent, it acts by reducing the levels of tumor necrosis factor-a (TNF-a), interleukin-6 (IL-6), and prostaglandin E2 (PGE2), inhibiting cyclooxygenase-2 (COX-2) protein expression. |
| M3657 | Pepstatin A (Pepstatin) | Pepstatin A (Pepstatin) is a specific inhibitor of aspartic proteases produced by actinomycetes, which can inhibit hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease with IC50 values of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM, respectively. |
| M3561 | Geldanamycin | Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association. |
| M3540 | Oxytetracycline | Oxytetracycline (Terramycin) was the second of the broad-spectrum tetracycline group of antibiotics to be discovered. |
| M3496 | Podophyllotoxin | Podophyllotoxin (Podofilox) is a lignan (lignans) found in podophyllin resin from the roots of podophyllum plants. |
| M3460 | Colchicine | Colchicine is a natural product extracted from Colchicum spp. It is also a tubulin inhibitor and microtubule disruptor with an IC50 of 3 nM for inhibition of microtubule polymerization, and a competitive antagonist of α3 glycine receptors (GlyRs). Colchicine is also a competitive antagonist of α3 Glycine receptors (GlyRs) and has been used in gout research. |
| M3452 | Quinine hydrochloride Dihydrate | Quinine hydrochloride Dihydrate is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste. |
| M3416 | Mycophenolic acid | Mycophenolic acid is an immunosuppressant agent used to prevent rejection in organ transplantation. |
| M3406 | Quinidine | Quinidine is a pharmaceutical agent that acts as a class I antiarrhythmic agent. |
| M3377 | Honokiol | Honokiol is the active principle of magnolia extract that inhibits Akt-phosphorylation and promotes ERK1/2 phosphorylation. |
| M3351 | Methoxsalen | Methoxsalen (Oxsoralen) a naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia, is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight. |
| M3332 | Alizarin | Alizarin strongly inhibits P450 isoform CYP1A1, CYP1A2 and CYP1B1 with IC50 of 6.2 μM, 10.0 μM and 2.7 μM, respectively; weakly inhibits CYP2A6 and CYP2E1, and does not inhibit CYP2C19, CYP3A4 and CYP3A5. |
| M3327 | Genipin | Genipin is an active aglycone derived from an iridoid glycoside called geniposide, which is found in the fruit of Gardenia jasminoides Ellis. Genipin has a variety of bioactivities, including modulation on proteins, antitumor, anti-inflammation, immunosuppression, antithrombosis, and protection of hippocampal neurons. |
| M3306 | Daphnetin | Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor, inhibits EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively, also known to exhibit anti-inflammatory and anti-oxidant activities. |
| M3253 | (-)-Huperzine A | (-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4. |
| M3208 | Geniposide | Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis. |
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