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Cynaroside

Cat. No. M3926

All AbMole products are for research use only, cannot be used for human consumption.

Cynaroside Structure
Synonym:

Luteolin-7-O-D-glucopyranoside

Size Price Availability Quantity
5mg USD 90  USD90 In stock
10mg USD 130  USD130 In stock
25mg USD 245  USD245 In stock
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Quality Control & Documentation
Biological Activity

Cynaroside pretreatment significantly reduced the apoptotic rate by enhancing the endogenous anti-oxidative activity of superoxide dismutase, glutathione peroxidase, and catalase, thereby inhibiting intracellular reactive oxygen species (ROS) generation. Moreover, cynaroside moderated H(2) O(2) -induced disruption of mitochondrial membrane potential, increased the expression of anti-apoptotic protein Bcl-2 while decreased the expression of pro-apoptotic protein Bax, and thereby inhibited the release of apoptogenic factors (cytochrome c and smac/Diablo) from mitochondria in H9c2 cells. Cynaroside prevents H(2) O(2) -induced apoptosis in H9c2 cell by reducing the endogenous production of ROS, maintaining mitochondrial function, and modulating the JNK and P53 pathways.

Chemical Information
Molecular Weight 448.38
Formula C21H20O11
CAS Number 5373-11-5
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Sun X, et al. J Cell Biochem. Protective effects of cynaroside against H₂O₂-induced apoptosis in H9c2 cardiomyoblasts.

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Keywords: Cynaroside, Luteolin-7-O-D-glucopyranoside supplier, Akt, inhibitors, activators

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