About 30 results found for searched term "Akt" (0.079 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4988 | AKT inhibitor VIII | Akt |
| Akt Inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity (IC50 = 58 nM, 210 nM, and 2.12 μM; respectively). | ||
| M58584 | (E)-Akt inhibitor-IV | Akt |
| CS-1992 | ||
| (E)-Akt inhibitor-IV is a PI3K-Akt inhibitor, with potent cytotoxic. | ||
| M14832 | AKT-IN-1 | Akt |
| AKT-IN-1 is an allosteric AKT inhibitor with an IC50 of 1.042 μM. | ||
| M14833 | AKT Kinase Inhibitor | Akt |
| AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity. | ||
| M27611 | PF-AKT400 | Akt |
| AKT protein kinase inhibitor | ||
| PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM). | ||
| M28416 | AKT-IN-6 | Akt |
| AKT-IN-6 (Example 13) is a potent Akt inhibitor. AKT-IN-6 inhibits Akt1, Akt2 and Akt3 with IC50 values < 500nM, respectively. | ||
| M29837 | Akt3 degrader 1 | Akt |
| Akt3 degrader 1 (compound 12l) is a selective Akt3 degrader that overcomes Osimertinib-induced resistance in H1975OR NSCLC cells. Akt3 degrader 1 also has anti-proliferative activity and significantly inhibits tumour growth in mice. Akt3 degrader 1 can be used in the study of drug-resistant non-small cell lung cancer. | ||
| M30367 | Akt1/Akt2-IN-2 | Akt |
| Akt1/Akt2-IN-2 (compound 7) is an allosteric dual Akt1 and Akt2 inhibitor (IC50=138 nM and 212 nM, respectively). Akt1/Akt2-IN-2 increases activity of caspase-3, and inhibits viability of a number of tumor cells. | ||
| M30829 | Akt1/Akt2-IN-1 | Akt |
| Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM), with potent and balanced activity. | ||
| M31261 | Akt1&PKA-IN-1 | Akt |
| Akt1&PKA-IN-1 is a potent dual Akt/PKA inhibitor with IC50 values of 0.03 , 0.11 μM, and 9.8 μM for PKAa, Akt, and CDK2, respectively. Akt1&PKA-IN-1 is selective for cyclin-dependent kinase 2 (CDK2). | ||
| M42148 | Akt/NF-κB/MAPK-IN-1 | p38 MAPK |
| Akt/NF-κB/MAPK-IN-1 is a potent and orally active inhibitor against NO (IC50=7.70 μM) with no significant toxicity. | ||
| M43366 | AKT-IN-14 free base | Akt |
| AKT-IN-14 free baseis a potent AKTinhibitor with the IC50 values of <0.01 nM, 1.06 nM and 0.66 nM for AKT1, AKT2, AKT3, respectively. | ||
| M43367 | AKT-IN-14 | Akt |
| AKT-IN-14 is a potent AKTinhibitor with the IC50 values of <0.01 nM, 1.06 nM and 0.66 nM for AKT1, AKT2, AKT3, respectively. | ||
| M43369 | Tubulin/AKT1-IN-1 | Akt |
| Tubulin/AKT1-IN-1 is an inhibitor of tubulin polymerization and AKT pathway activation. | ||
| M43370 | AKT-IN-18 | Akt |
| AKT-IN-18, an inhibitor of Akt, inhibits Akt with an IC50 of 69.45 μΜ in A549 cells. | ||
| M43375 | AKT-IN-17 | Akt |
| AKT-IN-17 is a AKt inhibitor. | ||
| M49742 | AKT-IN-11 | Akt |
| AKT-IN-11 is one of the most effective antibacterial agents against human hepatoma BEL-7402 cell line with an IC50 value of 1.15μM. | ||
| M49772 | Akt/ROCK-IN-1 | ROCK |
| Akt/ROCK-IN-1 (B12) is a dual inhibitor for Akt and ROCK, with the IC50s of 0.023 nM and 1.47 nM, respectively. | ||
| M50433 | TAT-TCL1-Akt-in | Akt |
| TAT-TCL1-Akt-in is an Akt inhibitor. | ||
| M50436 | Akt/SKG Substrate Peptide | Akt |
| Akt/SKG Substrate Peptide is a synthetic peptide suitable as a substrate for Akt/PKB, which is not phosphorylated by p70S6K or MAPK1. | ||
| M50778 | Akt Substrate | Others |
| Akt Substrate (Akt/SKG substrate) is a 7 amino acid synthetic peptide suitable as a substrate for Akt. | ||
| M55555 | PI3K/Akt/CREB activator 1 | PI3K |
| compound AE-18 | ||
| PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. | ||
| M57077 | PI3K/AKT-IN-1 | PI3K |
| PI3K/AKT-IN-1 is an effective PI3K/AKT dual inhibitor (IC50 of 6.99, 4.01 and 3.36 μM for PI3Kγ, PI3Kδ and AKT, respectively). | ||
| M57074 | PI3K/Akt/mTOR-IN-2 | PI3K |
| PI3K/Akt/mTOR-IN-2 is a PI3K/AKT/mTOR pathway inhibitor. | ||
| M60615 | Akt Mouse Pre-designed siRNA Set | siRNA |
| Akt serine/threonine kinase 1 | ||
| Mouse Akt Pre-designed siRNA Set contains three designed siRNAs for Akt gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 11651 | ||
| M60718 | Beclin1 Mouse Pre-designed siRNA Set | siRNA |
| Akt serine/threonine kinase 1 | ||
| Mouse Beclin1 Pre-designed siRNA Set contains three designed siRNAs for Beclin1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 11651 | ||
| M61337 | akt1 Human Pre-designed siRNA Set | siRNA |
| AKT serine/threonine kinase 1 | ||
| Human akt1 Pre-designed siRNA Set contains three designed siRNAs for akt1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 207 | ||
| M61369 | Akt1 Mouse Pre-designed siRNA Set | siRNA |
| Akt serine/threonine kinase 1 | ||
| Mouse Akt1 Pre-designed siRNA Set contains three designed siRNAs for Akt1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 11651 | ||
| M62927 | TCL1A Human Pre-designed siRNA Set | siRNA |
| TCL1 family AKT coactivator A | ||
| Human TCL1A Pre-designed siRNA Set contains three designed siRNAs for TCL1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 8115 | ||
| M63754 | akt Human Pre-designed siRNA Set | siRNA |
| AKT serine/threonine kinase 1 | ||
| Human akt Pre-designed siRNA Set contains three designed siRNAs for akt gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 207 | ||
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