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Akt3 degrader 1 (compound 12l) is a selective Akt3 degrader that overcomes Osimertinib-induced resistance in H1975OR NSCLC cells. Akt3 degrader 1 also has anti-proliferative activity and significantly inhibits tumour growth in mice. Akt3 degrader 1 can be used in the study of drug-resistant non-small cell lung cancer.
Molecular Weight | 885.19 |
Formula | C53H72N8O4 |
CAS Number | 2836342-69-7 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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