| Cat.No. | Name | Information |
|---|---|---|
| M3208 | Geniposide | Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis. |
| M2945 | Pimozide | Pimozide is an antagonist of 6-hydroxyapatide against 6-hydroxyapatide, with Ki values of 1.4 nM, 2.5 nM and 588 nM for 6-hydroxyapatide, D3 and D1 receptors, respectively. Pimozide also has a high affinity for α1-adrenoceptor. Ki value is 39 nM. Pimozide is also an inhibitor of STAT3 and STAT5, and piperimidate triggers ADCD in glioblastoma cell lines (LN-229, MZ-54, GOS-3 and U343) by inducing dephosphorylation and inactivation of mTORC1. |
| M2941 | Piceatannol | Piceatannol, a natural stilbene, is a selective Syk inhibitor and ~10-fold selectivity versus Lyn. |
| M2904 | Ouabain | Ouabain is a selective Na+/K+, -ATPase inhibitor, binds to α2 /α3 subunit with Ki of 41 nM/15 nM. |
| M2839 | Mequinol | Mequinol (4-Methoxyphenol) is a depigmentation agent. |
| M2816 | Lithocholic acid | Lithocholic acid is a bile acid that acts as a detergent to solubilize fats for absorption, can also activate the vitamin D receptor. |
| M2780 | Isovaleramide | Isovaleramide is an anticonvulsant molecule isolated from Valeriana pavonii, it inhibits the liver alcohol dehydrogenases. |
| M2762 | Hyoscyamine | Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM. |
| M2602 | Hydrastinine hydrochloride | Hydrastinine hydrochloride is a semisynthetic alkaloid from the hydrolysis of the alkaloid hydrastine, which was found naturally in small quantities in Hydrastis canadensis L. |
| M2579 | Catharanthine sulfate | Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM. |
| M2539 | Coumarin | Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties. |
| M2501 | Cepharanthine | Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production. |
| M2450 | Bergapten | Bergapten is a psoralen that can be photoactivated and is capable of crossing-linking DNA, covalently modifying proteins and lipids, and consequently inhibiting cell replication. |
| M2443 | Benzoic Acid | Benzoic acid is a colorless crystalline solid and a simple aromatic carboxylic acid, used as a food preservative. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi. |
| M2438 | Bekanamycin | Bekanamycin is an aminoglycoside antibiotic. |
| M2252 | Ellagic acid | Ellagic acid is a natural antioxidant as well as a potent, ATP-competitive inhibitor of CK2 and SHP2 with IC50 and Ki values of 40 nM and 20 nM, respectively.In addition, Ellagic acid exhibits antiproliferative activity and inhibition of topoisomerase II (Topoisomerase II). |
| M2226 | Melatonin | Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. |
| M2149 | Astragaloside A | Astragaloside A is a novel regulator of HIF-1α and angiogenesis through the PI3K/Akt pathway in HUVECs. |
| M2127 | Hesperadin | Hesperadin is an ATP-competitive inhibitor of Aurora B kinase with IC50 of 250 nM. Hesperadin inhibits the growth of Trypanosoma brucei by blocking nuclear division and cytokinesis. |
| M2009 | Teicoplanin | Teicoplanin is a long-acting glycopeptide antibiotic derived from actinomycetes that inhibits cell wall synthesis and interferes with the process of synthesizing new portions of peptidoglycan, and has a good inhibitory effect on gram-positive pathogens (including staphylococcal biofilms). |
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