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Glycyrrhizic acid

Cat. No. M3909

All AbMole products are for research use only, cannot be used for human consumption.

Glycyrrhizic acid Structure
Synonym:

NSC 167409; Glycyrrhizin

Size Price Availability Quantity
50mg USD 50  USD50 In stock
100mg USD 74  USD74 In stock
200mg USD 110  USD110 In stock
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Biological Activity

Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities. Glycyrrhizic acid may have potential as a therapeutic agent in cerebral ischemia by preventing oxidative stress. Glycyrrhizic acid would be a promising carrier for the oral delivery of PTX.

Chemical Information
Molecular Weight 822.94
Formula C42H62O16
CAS Number 1405-86-3
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yang FH, et al. Molecules. Bioavailability Enhancement of Paclitaxel via a Novel Oral Drug Delivery System: Paclitaxel-Loaded Glycyrrhizic Acid Micelles.

[2] Akman T, et al. Inflammation. The Neuroprotective Effect of Glycyrrhizic Acid on an Experimental Model of Focal Cerebral Ischemia in Rats.

[3] Fomina MK, et al. Ross Fiziol Zh Im I M Sechenova. [Effects of buspirone complex with glycyrrhizic acid on behavior of mice with anxious-depressive state].

[4] Wu CH, et al. J Agric Food Chem. Protective Effects of Glycyrrhizic Acid and 18β-Glycyrrhetinic Acid against Cisplatin-Induced Nephrotoxicity in BALB/c Mice.

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Keywords: Glycyrrhizic acid, NSC 167409; Glycyrrhizin supplier, HMGB1, inhibitors, activators

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