About 5 results found for searched term "HMGB1" (0.055 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M22496 | Recombinant Mouse HMGB1 Protein (HEK293, hFc Tag) | Recombinant Proteins |
| High-mobility group box 1; HMG-1 | ||
| The recombinant mouse HMGB1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 475 amino acids and has a calculated molecular mass of 53.3 kDa. High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family. HMGB1 is a DNA-binding nuclear protein, released actively following cytokine stimulation as well as passively during cell death. | ||
| M22497 | Recombinant Human HMGB1 Protein (E. coli, C-His) | Recombinant Proteins |
| High Mobility Group Box-1; rHuHMGB1 | ||
| Human High-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 30 kDa, 215 amino acid (a.a.) single chain polypeptide. | ||
| M41991 | HMGB1-IN-1 | HMGB1 |
| HMGB1-IN-1 inhibits the HMGB1/NF-κB/NLRP3 pathway and also exhibits strong NO inhibition in RAW264.7 cells with an IC50 value of 15.9 ± 0.6 μM. anti-inflammatory activity. | ||
| M42898 | HMGB1-IN-2 | HMGB1 |
| HMGB1-IN-2 is an inhibitor of highly conserved nuclear protein (HMGB1), showing NO inhibitory effect with IC50 value of 20.2 μM in RAW264.7 cells. | ||
| M55397 | Recombinant Human HMGB1 Protein (E. coli) | Recombinant Proteins |
| High Mobility Group Protein B1 | ||
| High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses. | ||
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