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HMGB1 High mobility group protein B1

Cat.No.  Name Information
M3909 Glycyrrhizic acid Glycyrrhizic acid is a widely used anti-inflammatory agent isolated from the licorice root.
M3571 Ammonium Glycyrrhizinate Ammonium Glycyrrhizinate is a unique product derived from Licorice root and has an extremely sweet taste.
M45255 HBP08 HBP08 is a high mobility group protein B1 (HMGB1) modulator that can be used in studies related to inflammation.
M45254 18-mer-HP 18-mer-HP is a high mobility group protein B1 (HMGB1) modulator that can be used in studies related to acute liver failure.
M45253 AFX-2101 AFX-2101 is a high mobility group protein B1 (HMGB1) modulator for studies related to CNS trauma.
M45252 SB1703 SB1703 is a high mobility group protein B1 (HMGB1) modulator for melanoma-related studies.
M45251 SB17170 SB17170 is an HMGB1 modulator that can be used in studies related to solid tumors.
M42898 HMGB1-IN-2 HMGB1-IN-2 is an inhibitor of highly conserved nuclear protein (HMGB1), showing NO inhibitory effect with IC50 value of 20.2 μM in RAW264.7 cells.
M41991 HMGB1-IN-1 HMGB1-IN-1 inhibits the HMGB1/NF-κB/NLRP3 pathway and also exhibits strong NO inhibition in RAW264.7 cells with an IC50 value of 15.9 ± 0.6 μM. anti-inflammatory activity.
M30863 Inflachromene  Inflachromene, a microglial inhibitor, binds to HMGB1 and HMGB2 and exerts anti-inflammatory effects. Inflachromene effectively downregulates proinflammatory functions of HMGB and reduces neuronal damage. Inflachromene can be used for the research of neuroinflammatory disorders.
M27810 NecroX-7  NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research.




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