| Cat.No. | Name | Information |
|---|---|---|
| M3909 | Glycyrrhizic acid | Glycyrrhizic acid is a widely used anti-inflammatory agent isolated from the licorice root. |
| M3571 | Ammonium Glycyrrhizinate | Ammonium Glycyrrhizinate is a unique product derived from Licorice root and has an extremely sweet taste. |
| M45255 | HBP08 | HBP08 is a high mobility group protein B1 (HMGB1) modulator that can be used in studies related to inflammation. |
| M45254 | 18-mer-HP | 18-mer-HP is a high mobility group protein B1 (HMGB1) modulator that can be used in studies related to acute liver failure. |
| M45253 | AFX-2101 | AFX-2101 is a high mobility group protein B1 (HMGB1) modulator for studies related to CNS trauma. |
| M45252 | SB1703 | SB1703 is a high mobility group protein B1 (HMGB1) modulator for melanoma-related studies. |
| M45251 | SB17170 | SB17170 is an HMGB1 modulator that can be used in studies related to solid tumors. |
| M42898 | HMGB1-IN-2 | HMGB1-IN-2 is an inhibitor of highly conserved nuclear protein (HMGB1), showing NO inhibitory effect with IC50 value of 20.2 μM in RAW264.7 cells. |
| M41991 | HMGB1-IN-1 | HMGB1-IN-1 inhibits the HMGB1/NF-κB/NLRP3 pathway and also exhibits strong NO inhibition in RAW264.7 cells with an IC50 value of 15.9 ± 0.6 μM. anti-inflammatory activity. |
| M30863 | Inflachromene | Inflachromene, a microglial inhibitor, binds to HMGB1 and HMGB2 and exerts anti-inflammatory effects. Inflachromene effectively downregulates proinflammatory functions of HMGB and reduces neuronal damage. Inflachromene can be used for the research of neuroinflammatory disorders. |
| M27810 | NecroX-7 | NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research. |
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