Free shipping on all orders over $ 500

SB17170

Cat. No. M45251
SB17170 Structure
Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

SB17170 is an HMGB1 modulator that can be used in studies related to solid tumors.

Chemical Information
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Related HMGB1 Products
HBP08

HBP08 is a high mobility group protein B1 (HMGB1) modulator that can be used in studies related to inflammation.

18-mer-HP

18-mer-HP is a high mobility group protein B1 (HMGB1) modulator that can be used in studies related to acute liver failure.

AFX-2101

AFX-2101 is a high mobility group protein B1 (HMGB1) modulator for studies related to CNS trauma.

SB1703

SB1703 is a high mobility group protein B1 (HMGB1) modulator for melanoma-related studies.

HMGB1-IN-2

HMGB1-IN-2 is an inhibitor of highly conserved nuclear protein (HMGB1), showing NO inhibitory effect with IC50 value of 20.2 μM in RAW264.7 cells.

  Catalog
Abmole Inhibitor Catalog




Keywords: SB17170 supplier, HMGB1, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.